Results 51 to 60 of about 401,067 (279)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Some new families of compositions based on big part restrictions [PDF]
Discrete Mathematics Letters, 2022 Augustine O. Munagi, Mark Shattuck
doaj +1 more source
Number of spanning trees of some families of graphs generated by a triangle
Journal of Taibah University for Science, 2019 In mathematics, one always tries to get new structures from given ones. This also applies to the realm of graphs, where one can generate many new graphs from a given set of graphs.
S. N. Daoud
doaj +1 more source
Some Determinantal Expressions and Recurrence Relations of the Bernoulli Polynomials
Mathematics, 2016 In the paper, the authors recall some known determinantal expressions in terms of the Hessenberg determinants for the Bernoulli numbers and polynomials, find alternative determinantal expressions in terms of the Hessenberg determinants for the Bernoulli ...
Feng Qi, Bai-Ni Guo
doaj +1 more source
On the reciprocal sum of the fourth power of Fibonacci numbers
Open Mathematics, 2022 Let fn{f}_{n} be the nnth Fibonacci number with f1=f2=1{f}_{1}={f}_{2}=1. Recently, the exact values of ∑k=n∞1fks−1⌊{\left({\sum }_{k=n}^{\infty }\frac{1}{{f}_{k}^{s}}\right)}^{-1}⌋ have been obtained only for s=1,2s=1,2, where ⌊x⌋\lfloor x\
Hwang WonTae +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Supplementary Data from Local Recurrence after Breast-Conserving Therapy in Relation to Gene Expression Patterns in a Large Series of Patients [PDF]
, 2023 Bas Kreike +8 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Generating Special Curves for Cubic Polynomials
MathematicsAn algorithmic method is proposed to generate all cubic polynomials with a critical orbit relation. We generate curves (polynomials of parameters) that correspond to those functions with critical orbit relations.
Khudoyor Mamayusupov +4 more
doaj +1 more source