Results 81 to 90 of about 401,067 (279)

Recurrence of head and neck squamous cell carcinoma in relation to high-risk treatment volume [PDF]

open access: gold, 2021
Linda Nissi   +5 more
openalex   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Generalized Horadam Polynomials and Numbers

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2018
We consider the polynomials hn,m(x) (m ≥ 2) and the numbers hn,m (x = 1), which are the generalized Horadam polynomials and the generalized Horadam numbers, respectively. We also consider the polynomials h(s)n,m(x)- convolutions of the polynomials hn,m(x)
Djordjevic Snezana S.   +1 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

New Properties and Matrix Representations on Higher-Order Generalized Fibonacci Quaternions with q-Integer Components

open access: yesAxioms
In this paper, by using q-integers and higher-order generalized Fibonacci numbers, we define the higher-order generalized Fibonacci quaternions with q-integer components. We give some special cases of these newly established quaternions.
Can Kızılateş   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Cube Recurrence

open access: yes, 2004
We construct a combinatorial model that is described by the cube recurrence, a nonlinear recurrence relation introduced by Propp, which generates families of Laurent polynomials indexed by points in $\mathbb{Z}^3$.
Carroll, Gabriel D., Speyer, David E
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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