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Recurrent failure, the heartbreaking knowledge of couples who find it difficult to start or extend their families, is a baffling and excitedly distressing generative strength issue. Defined as the incidence of three or more successive pregnancy misfortunes before the 20th temporal length of the event or entity’s existence of a process of early ...
Cecilia Bottomley +2 more
openaire +2 more sources
Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen +13 more
wiley +1 more source
Why Doesn’t a Pregnant Woman Reject her Fetus [PDF]
Overview: Recurrent Pregnancy loss (RPL) occurs when a woman has three or more consecutive miscarriages; this phenomenon happens in about 1-3% of women. Why some women reject their unborn fetus and others carry theirs to term is still unclear.
Merry, Lisa
core +1 more source
Endometrial transcriptome in recurrent miscarriage and recurrent implantation failure [PDF]
The endometrium becomes receptive to the embryo only in the mid-luteal phase, but not other stages of the menstrual cycle. Endometrial factors play an important role in implantation.
Chan, Ting Fung +8 more
core +1 more source
Objective To investigate how women experience the initial period of a new pregnancy after suffering recurrent miscarriage (RM). Design A qualitative study, nested within a randomised controlled feasibility study of a coping intervention for RM, used semi-
Sarah Bailey +5 more
semanticscholar +1 more source
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe +8 more
wiley +1 more source
Diagnosis of antiphospholipid syndrome in routine clinical practice. [PDF]
The updated international consensus criteria for definite antiphospholipid syndrome (APS) are useful for scientific clinical studies. However, there remains a need for diagnostic criteria for routine clinical use.
Cohen, H +3 more
core +1 more source
Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage.
J. Brosens +7 more
semanticscholar +1 more source
Early evolutionary history of the seed
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman +2 more
wiley +1 more source
What treatments prevent miscarriage after recurrent pregnancy loss? [PDF]
Progesterone produces a small but significant decrease in miscarriage among pregnant women with 3 or more unexplained pregnancy losses (strength of recommendation [SOR]: A, based on a meta-analysis of 3 small randomized controlled trials [RCTs] with wide
Kelsberg, Gary +2 more
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