Results 41 to 50 of about 886,868 (333)

Effect of antithyroid antibodies on women with recurrent miscarriage: A meta‐analysis

American Journal of Reproductive Immunology, 2020
The effect of thyroid autoimmunity (TAI) on the prevalence of recurrent miscarriage (RM) is highly debatable. No meta‐analysis has been published in the past decade to investigate the impact of TAI on women with RM.
Jilai Xie, Lihong Jiang, A. Sadhukhan, Song-Qing Yang, Qiuping Yao, P. Zhou, Jinpeng Rao, M. Jin   +7 more
semanticscholar   +1 more source

Inflammation in recurrent miscarriage - a comprehensive perspective from uterine microenvironment and immune cell imbalance to therapeutic strategies.

Ginekologia Polska
Recurrent miscarriage, poses a significant challenge for many couples globally, the causes of which are not fully understood. Recent studies have shown the intricate link between uterine inflammation and recurrent miscarriages.
Mengsi Lin, Hui Xu, Jiaying Qiu
semanticscholar   +1 more source

Polycystic ovary syndrome and recurrent pregnancy loss, a review of literature

Frontiers in Endocrinology, 2023
ObjectivePCOS is a syndrome of ovarian dysfunction associated with recurrent pregnancy loss. Several correlating factors have been investigated that influence the risk of pregnancy loss in PCOS.
Rosa Wartena, Mushi Matjila
doaj   +1 more source

Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology.

Cochrane Database of Systematic Reviews, 2019
BACKGROUND Progesterone, a female sex hormone, is known to induce secretory changes in the lining of the uterus essential for successful implantation of a fertilized egg.
D. Haas, T. Hathaway, P. Ramsey
semanticscholar   +1 more source

Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage.

American Journal of Human Genetics, 2019
Recurrent miscarriage (RM) affects millions of couples globally, and half of them have no demonstrated etiology. Genome sequencing (GS) is an enhanced and novel cytogenetic tool to define the contribution of chromosomal abnormalities in human diseases ...
Z. Dong, Junhao Yan, Fengping Xu, Jianying Yuan, Hui Jiang, Huilin Wang, Haixiao Chen, Lei Zhang, Lingfei Ye, Jinjin Xu, Yuhua Shi, Zhenjun Yang, Ye Cao, Lingyun Chen, Qiaoling Li, Xia Zhao, Jiguang Li, Ao Chen, Wenwei Zhang, Hoi Gin Wong, Yingying Qin, Han Zhao, Yuan Chen, Pei Li, T. Ma, Wen-jing Wang, Y. K. Kwok, Yuan Jiang, A. Pursley, J. Chung, Yan Hong, K. Kristiansen, Huanming Yang, R. Piña-Aguilar, T. Leung, S. Cheung, C. Morton, K. Choy, Zi-jiang Chen   +38 more
semanticscholar   +1 more source

Assessing the sensitivity and the clinical impact of the 2023 ACR/EULAR classification criteria in Obstetric Antiphospholid Syndrome: findings from a multicenter Italian cohort with a long‐term follow‐up

Arthritis Care &Research, Accepted Article.
Objective To evaluate the sensitivity of the 2023 ACR/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS), and to assess their ability to identify patients at risk of future pregnancy complications.
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Progestagens in high-risk pregnancy. What we know today

Репродуктивная эндокринология, 2023
Miscarriage remains an important global problem: 23 million miscarriages are registered annually in the world, i.e. 44 pregnancy losses every minute, and the total risk of miscarriage is 15.3% of all pregnancies.
N.Y. Pedachenko, N.P. Goncharuk, E.F. Chaikivska, T.F. Tatarchuk, T.M. Tutchenko   +4 more
doaj   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

Advanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li, Jia‐Hui Huang, Jin‐E Yang, Yi‐Hang Li, Juan‐Zhen Hong, Ting‐Ting Wang, Ying‐Lei Chi, Meng‐Zhi Wu, Wei Wang, Ying Zhu, Shi‐Mei Zhuang   +10 more
wiley   +1 more source

The lncRNA ANRIL Gene rs2151280 GG Genotype is Associated with Increased Susceptibility to Recurrent Miscarriage in a Southern Chinese Population

Journal of Inflammation Research, 2021
Di Che,1,* Zhenzhen Fang,2,* Hanran Mai,1,* Yufen Xu,1 LanYan Fu,1 Huazhong Zhou,1 Linyuan Zhang,1 Lei Pi,1 Xiaoqiong Gu1 1Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s ...
Che D, Fang Z, Mai H, Xu Y, Fu L, Zhou H, Zhang L, Pi L, Gu X   +8 more
doaj