Results 21 to 30 of about 911,944 (331)

Dysfunction of Shh signaling activates autophagy to inhibit trophoblast motility in recurrent miscarriage

Experimental and Molecular Medicine, 2021
In early pregnancy, the placenta anchors the conceptus and supports embryonic development and survival. This study aimed to investigate the underlying functions of Shh signaling in recurrent miscarriage (RM), a serious disorder of pregnancy.
Yibin Pan, Lili Yan, Qiaoqiao Chen, Cheng Wei, Y. Dai, X. Tong, Haiyan Zhu, Meifei Lu, Yanling Zhang, Xiao-ying Jin, Tai Zhang, Xiaona Lin, F. Zhou, Songying Zhang   +13 more
semanticscholar   +1 more source

A hidden cause of infertility in hypothyroid patients [PDF]

, 2020
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy, Allam, Magdy Mohamed, Barakat, Sherine Samir, El-Zawawy, Hanaa Tarek, Saleh, Rasha Noureldin M.   +4 more
core   +1 more source

Lived experience of recurrent miscarriage: women and their partners’ experience of subsequent pregnancy and support within an NHS specialist clinic – a qualitative study

BMJ Open, 2023
Objective This study aims to describe the lived experiences of couples with a history of recurrent miscarriage in subsequent pregnancies and their perception of clinic support and cytogenetic investigations.Design A qualitative interview study with a ...
Debra Bick, Bronwyn Harris, Siobhan Quenby, Amelia Hawkes, Rebecca Claire Shields, Jo Parsons   +5 more
doaj   +1 more source

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.), Brosens, Jan J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Fishwick, Katherine, Fujihara, Risa, Kimani, Peter K., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Polanco, Angela, Quenby, Siobhan, Takeda, Satoru, Tewary, Shreeya   +13 more
core   +1 more source

Effect of Happiness Counseling on Depression, Anxiety, and Stress in Women with Recurrent Miscarriage

International Journal of Women's Health, 2021
Purpose This study investigated the effectiveness of a happiness counseling program on depression, anxiety, and stress in pregnant women with a history of recurrent miscarriage.
N. Elsharkawy, S. Mohamed, M. H. Awad, M. M. Ouda   +3 more
semanticscholar   +1 more source

‘An extra level of kind of torment’: Views and experiences of recurrent miscarriage care during the initial phases of COVID‐19 in Ireland—A qualitative interview study

Health Expectations, 2023
Introduction Maternity services underwent much change during the COVID‐19 pandemic. Research on the impact on miscarriage care and experiences during this time is sparse.
Rebecca Dennehy, Marita Hennessy, Jennifer Ui Dhubhgain, Con Lucey, Keelin O′Donoghue   +4 more
doaj   +1 more source

Insulin resistance in women with recurrent miscarriage: a systematic review and meta-analysis

BMC Pregnancy and Childbirth, 2021
Purpose This review aimed to investigate the association of insulin resistance (IR) in women with recurrent pregnancy loss compared to women with normal pregnancy history.
Wangyu Cai, Xi Luo, Houyi Lv, Kaiyou Fu, Jian Xu   +4 more
semanticscholar   +1 more source

FEATURES OF MONOCYTE POLARIZATION AT DIFFERENT OUTCOMES IN WOMEN WITH RECURRENT MISCARRIAGE

Медицинская иммунология, 2021
Currently, in the pathogenesis of recurrent miscarriage, a special role is given to immunological factors, in particular the role of innate immunity. The aim of the study was to assess the relative content of monocytes in the peripheral blood producing ...
E. V. Grigushkina, N. Yu. Sotnikova, N. V. Kroshkina, A. I. Malyshkina, I. E. Talanova   +4 more
doaj   +1 more source

Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester [PDF]

, 2009
Objectives: Defective implantation is a mechanism for recurrent pregnancy loss (RPL). We sought to determine whether the serum expression of human relaxin-2 (RLX) is impaired in women with a history of RPL.
Bogic, Bogic, Carp, Craig, Dilly O.C. Anumba, Emmer, Gardosi, Goldsmith, Hollis, Jauniaux, Jivraj, Johnson, Johnson, Laird, MacLennan, Maynard, Mtiraoui, Nicolaides, Palomba, Parry, Petersen, Piccinni, Prakash, Saad El Gelany, Sakbun, Salim, Sarah L. Elliott, Seki, Tin C. Li, Unemori, Yki-Jarvinen   +30 more
core   +2 more sources

Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal [PDF]

, 2008
BACKGROUND: The prevalence of congenital uterine anomalies in women with reproductive failure remains unclear, largely due to methodological bias. The aim of this review is to assess the diagnostic accuracy of different methodologies and estimate the ...
Cocksedge, K.A., Li, T-C., Saravelos, S.H.   +2 more
core   +1 more source