Results 41 to 50 of about 494,025 (276)

Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels

BMC Immunology, 2019
Background Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage.
Li Zhu, Mostafa Aly, Ruben Jeremias Kuon, Bettina Toth, Haihao Wang, Hristos Karakizlis, Rolf Weimer, Christian Morath, Eman Ibrahim, Naruemol Ekpoom, Gerhard Opelz, Volker Daniel   +11 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Hyaluronan–binding protein 2 (HABP2) gene variation in women with recurrent miscarriage

BMC Women's Health, 2018
Background Idiopathic recurrent miscarriage, defined as three or more consecutive miscarriages, is a distressing early pregnancy complication. Although, the etiology of recurrent miscarriage is still unknown, an aberrant regulation of the endometrial ...
Frida Husseini-Akram, Sally Haroun, Signe Altmäe, Lottie Skjöldebrand-Sparre, Helena Åkerud, Inger Sundström Poromaa, Britt-Marie Landgren, Anneli Stavreus-Evers   +7 more
doaj   +1 more source

Immunomodulators to treat recurrent miscarriage [PDF]

, 2014
Recurrent miscarriage is a reproductive disorder affecting many couples. Although several factors are associated with recurrent miscarriage, in more than 50% of the cases the cause is unknown.
Sicco A. Scherjon, Jelmer R. Prins, Tom E.C. Kieffer, Kieffer, Tom E.C., Prins, Jelmer R.; id_orcid, Prins, Jelmer R., Scherjon, Sicco A.   +6 more
core   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

The lncRNA ANRIL Gene rs2151280 GG Genotype is Associated with Increased Susceptibility to Recurrent Miscarriage in a Southern Chinese Population

Journal of Inflammation Research, 2021
Di Che,1,* Zhenzhen Fang,2,* Hanran Mai,1,* Yufen Xu,1 LanYan Fu,1 Huazhong Zhou,1 Linyuan Zhang,1 Lei Pi,1 Xiaoqiong Gu1 1Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s ...
Che D, Fang Z, Mai H, Xu Y, Fu L, Zhou H, Zhang L, Pi L, Gu X   +8 more
doaj  

Decreased endometrial vascularity and receptivity in unexplained recurrent miscarriage patients during midluteal and early pregnancy phases

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To evaluate the predictive value of three-dimensional (3D)-power Doppler sonography on recurrent miscarriage. Materials and methods: The study patients were divided into a recurrent miscarriage group (30 cases) and a normal pregnancy group (21
Shu-Yin Tan, Fu Hang, Gowreesunkur Purvarshi, Min-Qing Li, Da-Hua Meng, Ling-Ling Huang   +5 more
doaj   +1 more source

Progestagens in high-risk pregnancy. What we know today

Репродуктивная эндокринология, 2023
Miscarriage remains an important global problem: 23 million miscarriages are registered annually in the world, i.e. 44 pregnancy losses every minute, and the total risk of miscarriage is 15.3% of all pregnancies.
N.Y. Pedachenko, N.P. Goncharuk, E.F. Chaikivska, T.F. Tatarchuk, T.M. Tutchenko   +4 more
doaj   +1 more source

Soluble Flt-1 and PlGF: new markers of early pregnancy loss? [PDF]

, 2011
Recent data have indicated a relationship between placental oxygen and angiogenic protein levels in the first trimester of normal pregnancies. Our objective was to investigate if maternal serum levels of angiogenic factors Soluble vascular endothelial ...
Michelle Swer, Muttukrishna, S, Suri, S, Jurkovic, Davor, Jamil, Amna, Swer, Michelle, Suri, Sangeeta, Sangeeta Suri, Jauniaux, E, Gangooly, Subrata, Gangooly, S, Calleja-Agius, Jean, Jamil, A, Amna Jamil, Ludlow, H, Muttukrishna, Shanthi, Jurkovic, D, Helen Ludlow, Davor Jurkovic, Calleja-Agius, J, Eric Jauniaux, Subrata Gangooly, Swer, M, Jean Calleja-Agius, Jauniaux, Eric R.M., Ludlow, Helen, Shanthi Muttukrishna, Jamil Amna, Suri Sangeeta, Calleja-Agius Jean, Muttukrishna Shanthi, Gangooly Subrata, Jauniaux, Eric, Swer Michelle, Jurkovic Davor, Ludlow Helen, Jauniaux Eric   +36 more
core   +2 more sources