Results 11 to 20 of about 911,944 (331)

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
AJ Wilcox, AM Musters, Annemieke Kavelaars, B Gellersen, Birgit Gellersen, Charlotte H. E. Weimar, Cobi J. Heijnen, Cornelis B. Lambalk, CW Redman, DK Gardner, E Vanneste, EB Baart, G Teklenburg, G Teklenburg, GM Stirrat, H Carp, HJ Leese, HJ Leese, HM Picton, IC Lakovschek, Jan J. Brosens, JD Aplin, JL Evers, Johanna M. T. de Vreeden-Elbertse, M Bielanska, M Gonzalez, M Salker, N Mansouri-Attia, Nick S. Macklon, NS Macklon, PJ Stokes, R Rai, RM Popovici, S Grewal, S Grewal, S Quenby   +35 more
core   +9 more sources

Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis

Human Reproduction Update, 2022
BACKGROUND Uterine natural killer cells (uNK) are the most abundant lymphocytes found in the decidua during implantation and in first trimester pregnancy.
E. Woon, Orene Greer, N. Shah, D. Nikolaou, Mark Johnson, Victoria Male   +5 more
semanticscholar   +1 more source

Expression of tissue factor and tissue factor pathway inhibitors during ovulation in rats: a relevance to the ovarian hyperstimulation syndrome

Reproductive Biology and Endocrinology, 2021
Background Blood coagulation has been associated with ovulation and female infertility. In this study, the expression of the tissue factor system was examined during ovulation in immature rats; the correlation between tissue factor and ovarian ...
You Jee Jang, Hee Kyung Kim, Bum Chae Choi, Sang Jin Song, Jae Il Park, Sang Young Chun, Moon Kyoung Cho   +6 more
doaj   +1 more source

Single-cell Immune Landscape of Human Recurrent Miscarriage

Genomics, Proteomics & Bioinformatics, 2021
Successful pregnancy in placental mammals substantially depends on the establishment of maternal immune tolerance to the semi-allogenic fetus. Disorders in this process are tightly associated with adverse pregnancy outcomes including recurrent ...
Feiyang Wang, Wentong Jia, M. Fan, Xuan Shao, Zhilang Li, Yongjie Liu, Yeling Ma, Yu-Xia Li, Rong Li, Q. Tu, Yan-Ling Wang   +10 more
semanticscholar   +1 more source

Decreased Ovarian Reserve Predicts Inexplicability of Recurrent Miscarriage? A Retrospective Analysis. [PDF]

PLoS ONE, 2016
OBJECTIVE:To evaluate anti-Mullerian hormone, basal follicle stimulating hormone, luteinizing hormone, estradiol, and female age in women with recurrent miscarriage and to compare women with explained and idiopathic recurrent miscarriage.
Sophie Pils, Regina Promberger, Stephanie Springer, Elmar Joura, Johannes Ott   +4 more
doaj   +1 more source

Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage.

Seminars in Cell and Developmental Biology, 2022
Compared to most mammals, human pregnancy is unusual in that it involves chromosomally diverse embryos, cyclical breakdown and regeneration of the uterine mucosa, and intimate integration of fetal and maternal cells at the uteroplacental interface.
J. Brosens, P. Bennett, V. Abrahams, R. Ramhorst, A. Coomarasamy, S. Quenby, E. Lucas, R. McCoy   +7 more
semanticscholar   +1 more source

Recurrent miscarriage: evidence to accelerate action.

The Lancet, 2021
Women who have had repeated miscarriages often have uncertainties about the cause, the likelihood of recurrence, the investigations they need, and the treatments that might help.
A. Coomarasamy, Rima K. DHILLON-SMITH, Argyro Papadopoulou, M. Al-Memar, J. Brewin, V. Abrahams, A. Maheshwari, O. Christiansen, M. Stephenson, M. Goddijn, O. Oladapo, C. Wijeyaratne, D. Bick, H. Shehata, R. Small, P. Bennett, L. Regan, R. Rai, T. Bourne, R. Kaur, Oonagh Pickering, J. Brosens, A. Devall, I. Gallos, S. Quenby   +24 more
semanticscholar   +1 more source

Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review.

Reproductive Biomedicine Online, 2021
Recurrent miscarriage affects 1-2% of women of reproductive age, depending on the definition used. A systematic review was conducted to identify, appraise and describe clinical practice guidelines (CPG) published since 2000 for the investigation ...
M. Hennessy, R. Dennehy, S. Meaney, L. Linehan, D. Devane, R. Rice, K. O'Donoghue   +6 more
semanticscholar   +1 more source

Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage

Frontiers in Immunology, 2021
An appropriate development of the placenta consisting of trophoblast cell migration, invasion, proliferation, and apoptosis, is essential to establishing and maintaining a successful pregnancy.
Jiayu Wang, Jinli Ding, Sainan Zhang, Xin Chen, Si-si Yan, Yan Zhang, Tailang Yin   +6 more
semanticscholar   +1 more source

The Role of Uterine Natural Killer Cells on Recurrent Miscarriage and Recurrent Implantation Failure: From Pathophysiology to Treatment

Biomedicines, 2021
Uterine natural killer (uNK) cells constitute a unique uterine leucocyte subpopulation facilitating implantation and maintaining pregnancy. Herein, we critically analyze current evidence regarding the role of uNK cells in the events entailed in recurrent
K. Sfakianoudis, A. Rapani, S. Grigoriadis, A. Pantou, E. Maziotis, Georgia Kokkini, Chrysanthi Tsirligkani, S. Bolaris, K. Nikolettos, M. Chronopoulou, K. Pantos, M. Simopoulou   +11 more
semanticscholar   +1 more source