Results 111 to 120 of about 3,951 (305)
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
CoRR, 2019 The way how recurrently connected networks of spiking neurons in the brain acquire powerful information processing capabilities through learning has remained a mystery. This lack of understanding is linked to a lack of learning algorithms for recurrent networks of spiking neurons (RSNNs) that are both functionally powerful and can be implemented by ...
Guillaume Bellec +5 more
openaire +3 more sources
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Sequence-discriminative training of deep neural networks
, 2013 Sequence-discriminative training of deep neural networks (DNNs) is investigated on a 300 hour American English conversational telephone speech task. Different sequence-discriminative criteria ndash;- maximum mutual information (MMI), minimum phone error (
Ghoshal, Arnab +3 more
core
Toward a dynamical systems analysis of neuromodulation [PDF]
, 2004 This work presents some first steps toward a more thorough understanding of the control systems employed in evolutionary robotics. In order to choose an appropriate architecture or to construct an effective novel control system we need insights into
Bullock, S. +5 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Does money matter in inflation forecasting? [PDF]
This paper provides the most fully comprehensive evidence to date on whether or not monetary aggregates are valuable for forecasting US inflation in the early to mid 2000s.
Graham Kendall +5 more
core
Turing Computability With Neural Nets
, 1991 . This paper shows the existence of a finite neural network, made up of sigmoidal neurons, which simulates a universal Turing machine. It is composed of less than 10 5 synchronously evolving processors, interconnected linearly.
Sontag, Eduardo D. +3 more
core +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source