Results 171 to 180 of about 894,811 (216)

Colchicine for recurrent pericarditis in children

Acta Paediatrica, 1998
The incidence of recurrence of acute pericarditis in children varies from 15% to 30% and is accompanied by a high morbidity. Various treatment modalities have been used with variable success rates and side effects. La Serna et al. (Lancet 1987; 26: 1517) were the first to treat adults with recurrent pericarditis with colchicine, and were followed by ...
A, Yazigi, L C, Abou-Charaf
openaire   +2 more sources

New developments in the management of recurrent pericarditis.

Canadian Journal of Cardiology, 2023
Recurrent pericarditis is a common and troublesome complication that affects 15 to 30% of patients with a previous episode of pericarditis. However, the pathogenesis of these recurrences is not well understood, and most cases remain idiopathic.
M. Imazio, V. Mardigyan, A. Andreis, L. Franchin, M. De Biasio, Valentino Collini   +5 more
semanticscholar   +1 more source

Interleukin-1 Blockers for the Treatment of Recurrent Pericarditis: Pathophysiology, Patient-Reported Outcomes, and Perspectives

Journal of Cardiovascular Pharmacology, 2023
Supplemental Digital Content is Available in the Text. Abstract Recurrent pericarditis (RP) is the most troublesome complication of acute pericarditis reflecting an unresolving inflammation of the pericardial sac around the heart and associated with ...
G. Thomas, A. Bonaventura, A. Vecchié, B. V. Van Tassell, M. Imazio, Allan L. Klein, S. Luis, A. Abbate   +7 more
semanticscholar   +1 more source

Acute and Recurrent Pericarditis

2014
Acute and recurrent pericarditis are the most common disorders involving the pericardium. There are few available epidemiological data and the exact incidence and prevalence of acute and recurrent pericarditis are unknown. However, acute pericarditis is recorded in about 0.1 % of hospitalized patients and 5 % of patients admitted to the Emergency ...
openaire   +1 more source

Treatment of recurrent pericarditis with colchicine

European Heart Journal, 1994
Corticosteroid therapy, because of its frequent and severe side effects should be avoided if possible, and colchicine may be an effective substitute in steroid-dependent recurrent pericarditis. The aim of our study was to assess the usefulness of colchicine in recurrent pericarditis before initiating corticosteroid treatment.
A, Millaire, P, de Groote, E, Decoulx, L, Goullard, G, Ducloux   +4 more
openaire   +2 more sources

Treatment options to break the cycle of recurrent pericarditis

Current Opinion in Cardiology
Purpose of review This review provides a contemporary, evidence-based update on the pathophysiological mechanisms and rapidly evolving therapeutic options for recurrent pericarditis.
A. Raisinghani, S. A. Luis
semanticscholar   +1 more source

Addressing recurrent pericarditis: assessing patient and professional education needs

European Heart Journal
Nearly 40,000 people in the U.S. experience recurrent pericarditis with up to 90% of cases having no identifiable cause, often making the journey to diagnosis arduous.
A. Klein, T. Wang, B. Weber, A. Abbate, J. Salik, S. Kohnstamm, S. A. Luis, P. Cremer, M. Al-Kazaz, D. Shah, L. Wang, A. Sabet, R. Tadwalkar, A H A Addressing Recurrent Pericarditis Initiative Parti, A. H. A. Addressing Recurrent Pericarditis Staff   +14 more
semanticscholar   +1 more source

Colchicine for the prevention of recurrent pericarditis.

The Israel Medical Association journal : IMAJ, 2008
The most troublesome complication of acute pericarditis is recurrent episodes of pericardial inflammation, which occur in 15-32% of cases. It was recently found that viral infection has a major role, but in many cases the cause is unknown. The optimal method for prevention has not been fully established; accepted modalities include non-steroidal anti ...
Markel G, Imazio M, Brucato A, Adler Y
openaire   +2 more sources

Abstract 4140774: Pharmaceutically Manufactured Cannabidiol Demonstrates Clinically Relevant Reductions in Pericarditis Pain and C-Reactive Protein in Patients with Recurrent Pericarditis – the MAvERIC-Pilot Study

Circulation
Background: Recurrent pericarditis results from inflammasome activation and is associated with significant morbidity. Cannabidiol has been shown to block numerous inflammasome signaling pathways, including reducing transcription of pro-IL-1β and NLRP3,
Sushil Luis, Allan Klein, Paul C. Cremer, Antonio Abbate, J. Salik, G. Thomas, S. W. Haider, Tracy Hagerty, D. Lin, Thomas E Waggoner, Stephen Nicholls, Andrea B. Parker, A. Hamer   +12 more
semanticscholar   +1 more source

Goflikicept and Related IL-1 Inhibitors in the Treatment of Recurrent Pericarditis.

Cardiology in Review
Anticytokine biologics are a promising anti-inflammatory therapy for recurrent pericarditis. Several studies have proved the efficacy and safety of interleukin-1 (IL-1) inhibitors, such as anakinra and rilonacept in patients with recurrent pericarditis ...
Jared M Feldman, William H. Frishman, W. Aronow   +2 more
semanticscholar   +1 more source