Results 31 to 40 of about 894,811 (216)

Autoinflammatory Recurrent Pericarditis Associated with a New NLRP12 Mutation in a Male Adolescent [PDF]

Life, 2023
Idiopathic recurrent pericarditis (IRP) can be the hallmark of an autoinflammatory syndrome with recurrent attacks of chest pain and symptom-free intervals following an acute episode. The recurrence rate may be 35% in the pediatric population, frequently
Eliza Cinteza, Dan Stefan, Mihaela Adela Iancu, Andreea Ioan, Corina Maria Vasile, Radu Vatasescu, Alexis Cochino   +6 more
doaj   +2 more sources

Corticosteroids for Recurrent Pericarditis [PDF]

Circulation, 2008
We have known for decades that acute pericarditis may recur after apparent cure.1 In spite of recent advances, recurrence, after an initial attack of acute pericarditis, remains a challenge for many reasons. For example, the exact rate of recurrence is not known because many, if not most, cases go unreported, especially those that have a benign course ...
Massimo Imazio, Antonio Brucato, Silvia Maestroni   +2 more
exaly   +2 more sources

Clinical Utility of Rilonacept for the Treatment of Recurrent Pericarditis: Design, Development, and Place in Therapy. [PDF]

Drug Des Devel Ther
Recurrent pericarditis (RP) has been traditionally regarded as a “nightmare” for both clinicians and patients. Until approximately a decade ago, available treatments were thin on the ground with non-steroidal anti-inflammatory medications ...
Vlachakis PK, Theofilis P, Soulaidopoulos S, Lazarou E, Tsioufis K, Lazaros G.   +5 more
europepmc   +2 more sources

Problems of immunopathology and prospects for pharmacotherapy of idiopathic recurrent pericarditis: Using an interleukin 1 inhibitor (Anakinra)

Научно-практическая ревматология, 2023
Pericarditis, a clinical syndrome characterized by inflammation and thickening of the pericardium, is one of the most common forms of inflammatory diseases of the cardiovascular system.
E. L. Nasonov, Z. N. Sukmarova, T. V. Popkova, B. S. Belov   +3 more
doaj   +2 more sources

Decrease in Hemoglobin Levels during Acute Attacks in Patients with Idiopathic Recurrent Pericarditis: A Model of Anemia in Acute Disease. [PDF]

J Clin Med
Background/Objectives: Anemia during acute inflammation is not well described in the literature. We aimed to study whether patients develop a transient hemoglobin decrease during an acute attack of recurrent pericarditis.
Casarin F, Mascolo R, Motta I, Wu MA, Bizzi E, Pedroli A, Dieguez G, Iacomelli G, Serati L, Duca L, Maestroni S, Tombetti E, Cappellini MD, Brucato A.   +13 more
europepmc   +2 more sources

Long-Standing Chronic Recurrent Pericarditis Managed With Advanced Diagnostic and Therapeutic Methods. [PDF]

JACC Case Rep
A 65-year-old woman with a history of idiopathic pericarditis presented with chronic recurrent pericarditis. Because of the inability to taper off anakinra without recurrent flares, she transitioned to rilonacept, which led to symptom abatement.
Majid M, Rosenzveig A, Daniela Arockiam A, Brands CK, Klein AL.   +4 more
europepmc   +2 more sources

Recurrent pericarditis

Tidsskrift for Den norske legeforening, 2023
Pericarditis is an important differential diagnosis in patients with chest pain. The two most common causes in the developed world are idiopathic pericarditis and inflammation following cardiac surgery or myocardial infarction. Recurrence of pericarditis affects up to 30 % of patients, half of whom experience multiple episodes, and approximately 10 ...
Dan Atar, Kjetil Steine, Tore Salte, Sverre Høie, Glenn Haugeberg, Einar Gude, Jostein Gleditsch, Pål Aukrust, Peter M. Andel   +8 more
openaire   +3 more sources

Pericarditis as an onset of cancer

Рациональная фармакотерапия в кардиологии, 2023
Pericarditis is an inflammation of the heart serous membrane of an infectious or non-infectious nature. Secondary pericardial effusion can be one of the few signs of cancer of the lung, pleura or breast in young people, while early treatment of the ...
D. F. Mesitskaya, S. A. Panov, D. A. Andreev, A. N. Volovchenko, A. Sh. Dumikyan   +4 more
doaj   +1 more source

Use of Anakinra in steroid dependent recurrent pericarditis: a case report and review of literature

Journal of Community Hospital Internal Medicine Perspectives, 2021
Non-steroidal anti-inflammatory drugs and colchicine are the cornerstone treatment for recurrent pericarditis. Corticosteroids are frequently used in patients with recurrent episodes of pericarditis.
Vinay Kumar Thallapally, Sonia Gupta, Sai Giridhar Gundepalli, Joseph Nahas   +3 more
doaj   +1 more source

Interleukin‐1 Trap Rilonacept Improved Health‐Related Quality of Life and Sleep in Patients With Recurrent Pericarditis: Results From the Phase 3 Clinical Trial RHAPSODY

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Recurrent pericarditis is characterized by painful flares and inflammation, which negatively impact health‐related quality of life. RHAPSODY (rilonacept inhibition of interleukin‐1 alpha and beta for recurrent pericarditis: a pivotal ...
Antonio Brucato, Michelle Z. Lim‐Watson, Allan Klein, Massimo Imazio, David Cella, Paul Cremer, Martin M. LeWinter, Sushil Allen Luis, David Lin, Dor Lotan, Massimo Pancrazi, Lucia Trotta, Brittany Klooster, Leighann Litcher‐Kelly, Liangxing Zou, Matt Magestro, Alistair Wheeler, John F. Paolini   +17 more
doaj   +1 more source