Results 31 to 40 of about 891,540 (202)

Anakinra-Dependent Recurrent Pericarditis: The Role of the R202Q Variant of the MEFV Gene. [PDF]

J Clin Med
Background: the role of the R202Q (c.605G>A, p.Arg202Gln) missense variant of the MEFV gene has been debated as either a benign polymorphism or a potentially pathogenic mutation.
Andreis A, Dossi FC, De Ferrari GM, Alunni G, Imazio M.   +4 more
europepmc   +2 more sources

Efficacy of colchicine in addition to anakinra in patients with recurrent pericarditis. [PDF]

Open Heart
Aim Anakinra, an anti IL-1 agent targeting IL-1 alfa and beta, is available for the treatment of recurrent pericarditis in cases with corticosteroid dependence and colchicine resistance after failure of conventional therapies.
Collini V, Andreis A, De Biasio M, De Martino M, Isola M, Croatto N, Lepre V, Cantarini L, Merlo M, Sinagra G, Abbate A, Lazaros G, Brucato A, Klein AL, Imazio M.   +14 more
europepmc   +2 more sources

Recurrent Pericarditis in Children and Adolescents [PDF]

Frontiers in Pediatrics, 2019
Recurrent pericarditis (RP) is a clinical syndrome characterized by recurrent attacks of acute pericardial inflammation. Prognosis quoad vitam is good, although morbidity might be significant, especially in children and adolescents.
Enrico Tombetti, Teresa Giani, Teresa Giani, Antonio Brucato, Rolando Cimaz, Rolando Cimaz   +5 more
doaj   +4 more sources

Corticosteroids for Recurrent Pericarditis [PDF]

Circulation, 2008
We have known for decades that acute pericarditis may recur after apparent cure.1 In spite of recent advances, recurrence, after an initial attack of acute pericarditis, remains a challenge for many reasons. For example, the exact rate of recurrence is not known because many, if not most, cases go unreported, especially those that have a benign course ...
Massimo Imazio, Antonio Brucato, Silvia Maestroni   +2 more
exaly   +2 more sources

Problems of immunopathology and prospects for pharmacotherapy of idiopathic recurrent pericarditis: Using an interleukin 1 inhibitor (Anakinra)

Научно-практическая ревматология, 2023
Pericarditis, a clinical syndrome characterized by inflammation and thickening of the pericardium, is one of the most common forms of inflammatory diseases of the cardiovascular system.
E. L. Nasonov, Z. N. Sukmarova, T. V. Popkova, B. S. Belov   +3 more
doaj   +2 more sources

Clinical Utility of Rilonacept for the Treatment of Recurrent Pericarditis: Design, Development, and Place in Therapy. [PDF]

Drug Des Devel Ther
Recurrent pericarditis (RP) has been traditionally regarded as a “nightmare” for both clinicians and patients. Until approximately a decade ago, available treatments were thin on the ground with non-steroidal anti-inflammatory medications ...
Vlachakis PK, Theofilis P, Soulaidopoulos S, Lazarou E, Tsioufis K, Lazaros G.   +5 more
europepmc   +2 more sources

Anakinra during pregnancy and lactation for corticosteroid-dependant colchicine-resistant recurrent pericarditis in a patient with neutralizing anti-interleukin-1 receptor antagonist antibodies: a case report. [PDF]

Eur Heart J Case Rep
Background Anakinra, an interleukin-1 receptor antagonist (IL-1 Ra), is a treatment option for recurrent pericarditis refractory to conventional therapy. However, some patients cannot discontinue anakinra treatment without relapse.
Cerne Cercek A, Gomiscek Novak A, Trojner Bregar A, Avcin T, Kessel C, Thurner L, Fadle N, Cercek M.   +7 more
europepmc   +2 more sources

Long-Standing Chronic Recurrent Pericarditis Managed With Advanced Diagnostic and Therapeutic Methods. [PDF]

JACC Case Rep
A 65-year-old woman with a history of idiopathic pericarditis presented with chronic recurrent pericarditis. Because of the inability to taper off anakinra without recurrent flares, she transitioned to rilonacept, which led to symptom abatement.
Majid M, Rosenzveig A, Daniela Arockiam A, Brands CK, Klein AL.   +4 more
europepmc   +2 more sources

Decrease in Hemoglobin Levels during Acute Attacks in Patients with Idiopathic Recurrent Pericarditis: A Model of Anemia in Acute Disease. [PDF]

J Clin Med
Background/Objectives: Anemia during acute inflammation is not well described in the literature. We aimed to study whether patients develop a transient hemoglobin decrease during an acute attack of recurrent pericarditis.
Casarin F, Mascolo R, Motta I, Wu MA, Bizzi E, Pedroli A, Dieguez G, Iacomelli G, Serati L, Duca L, Maestroni S, Tombetti E, Cappellini MD, Brucato A.   +13 more
europepmc   +2 more sources

Recurrent pericarditis

Tidsskrift for Den norske legeforening, 2023
Pericarditis is an important differential diagnosis in patients with chest pain. The two most common causes in the developed world are idiopathic pericarditis and inflammation following cardiac surgery or myocardial infarction. Recurrence of pericarditis affects up to 30 % of patients, half of whom experience multiple episodes, and approximately 10 ...
Dan Atar, Kjetil Steine, Tore Salte, Sverre Høie, Glenn Haugeberg, Einar Gude, Jostein Gleditsch, Pål Aukrust, Peter M. Andel   +8 more
openaire   +3 more sources