Results 71 to 80 of about 446,603 (195)

The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges

open access: yesFrontiers in Medicine, 2017
Recurrent pericarditis is a common complication of acute pericarditis (15–30%) for which, in most cases, no underlying etiology is found [idiopathic recurrent pericarditis (IRP)]. IRP is currently viewed as an autoinflammatory disease with characteristic
George Lazaros   +2 more
doaj   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Interleukin-1 Blockers in Recurrent and Acute Pericarditis: State of the Art and Future Directions

open access: yesMedicina
Diseases of the pericardium encompass a spectrum of conditions, including acute and recurrent pericarditis, where inflammation plays a pivotal role in the pathogenesis and clinical manifestations. Anti-inflammatory therapy indeed forms the cornerstone of
Antonella Gallo   +9 more
doaj   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang   +4 more
wiley   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra   +2 more
wiley   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum   +22 more
wiley   +1 more source

Infectious complications of dental procedures in dogs and cats, and the impact of antimicrobial prophylaxis: a systematic review

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To identify and describe available evidence pertaining to the local and systemic infectious complications in dogs and cats that have undergone dental procedures and the impact of peri‐procedural antimicrobial prophylaxis. Materials and Methods A systematic review was performed based on Preferred Reporting Items for Systematic Reviews and ...
J. S. Weese   +3 more
wiley   +1 more source

Advances in Imaging and Targeted Therapies for Recurrent Pericarditis: A Review

open access: yes, 2022
Importance: Pericarditis is the most common form of pericardial disease. Recurrence of pericarditis affects 15% to 30% of patients after the initial episode of pericarditis.
Imazio M.   +7 more
core   +1 more source

Expanding the Therapeutic Landscape of Pericarditis: A Systematic Review of the Use of Conventional Immunosuppressants

open access: yesMedicina
Background and Objectives: While interleukin-1 inhibitors represent the standard of care for refractory idiopathic recurrent acute pericarditis, current guidelines also endorse conventional immunosuppressive (IS) agents as potential alternatives. The use
Andrea Silvio Giordani   +14 more
doaj   +1 more source

The “Spiked Helmet Sign” on Electrocardiogram Following Left Ventricular Assist Device Implantation: A Case Report

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 6, November 2026.
The Spiked Helmet Sign on electrocardiogram after LVAD implantation serves as a critical early warning of localized pericardial hematoma and impending tamponade. Prompt recognition should trigger immediate echocardiographic evaluation, as demonstrated in this case, to guide urgent management.
Qin Qian, Ling Yin
wiley   +1 more source

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