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Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]

open access: goldCommunications Biology, 2020
During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.)   +12 more
core   +4 more sources

Recurrent pregnancy loss, psychological distress and wellbeing support for women: a mixed-methods analysis [PDF]

open access: yesBMC Women's Health
Background Research suggests multiple experiences of miscarriage, also known as recurrent pregnancy loss (RPL), may be associated with compounded risk for adverse mental health impacts.
Áine Aventin   +3 more
doaj   +2 more sources

Vaginal microbiome and recurrent pregnancy loss [PDF]

open access: yesInfection and Immunity
The joy of every mother is to survive a healthy pregnancy and give birth to a healthy baby. However, until today, many couples are finding it difficult to welcome a baby.
Xingxing Yuan   +3 more
doaj   +2 more sources

A combination of the HLA-DRB1*03 phenotype and low plasma mannose-binding lectin predisposes to autoantibody formation in women with recurrent pregnancy loss

open access: yesFrontiers in Immunology, 2023
IntroductionIt is documented that a series of autoantibodies can be detected with increased frequency in women with recurrent pregnancy loss (RPL) and they may impact the pregnancy prognosis negatively.
Caroline Nørgaard-Pedersen   +6 more
doaj   +1 more source

Dysbiosis of the Human Oral Microbiome During the Menstrual Cycle and Vulnerability to the External Exposures of Smoking and Dietary Sugar

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Physiological hormonal fluctuations exert endogenous pressures on the structure and function of the human microbiome. As such, the menstrual cycle may selectively disrupt the homeostasis of the resident oral microbiome, thus compromising oral health ...
Nagihan Bostanci   +19 more
doaj   +1 more source

Chronic Endometritis and Uterine Endometrium Microbiota in Recurrent Implantation Failure and Recurrent Pregnancy Loss

open access: yesBiomedicines, 2023
The aim of this study was to evaluate whether chronic endometritis (CE) and uterine endometrium microbiota were associated with repeated implantation failures (RIFs) and recurrent pregnancy losses (RPLs).
Kanako Takimoto   +4 more
doaj   +1 more source

Loss of Endometrial Plasticity in Recurrent Pregnancy Loss [PDF]

open access: yes, 2015
© 2015 AlphaMed Press.Menstruation drives cyclic activation of endometrial progenitor cells, tissue regeneration, and maturation of stromal cells, which differentiate into specialized decidual cells prior to and during pregnancy.
Brighton, PJ   +15 more
core   +4 more sources

Pregnancy loss is related to body mass index and prediabetes in early adulthood: Findings from Add Health

open access: yesPLoS ONE, 2022
Pregnancy loss, including miscarriage and stillbirth, affects 15–20% of pregnancies in the United States (US) annually. Accumulating evidence suggests that pregnancy loss is associated with a greater cardiovascular disease (CVD) burden later in life ...
Yamnia I. Cortés   +2 more
doaj   +2 more sources

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

open access: yes, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
AJ Wilcox   +35 more
core   +9 more sources

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