Results 11 to 20 of about 64,359 (215)

Pregnancy Loss and Cancer Risk: A Nationwide Observational Study

EClinicalMedicine, 2019
Background: Cancer is the second leading cause of death worldwide. Few studies have investigated if recurrent pregnancy loss is associated with an increased risk of cancer.
Anders P. Mikkelsen, Pia Egerup, Julie F.M. Ebert, Astrid M. Kolte, Henriette S. Nielsen, Øjvind Lidegaard   +5 more
doaj   +1 more source

Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions

Reproductive Biology and Endocrinology, 2018
Recurrent implantation failure (RIF) refers to cases in which women have had three failed in vitro fertilization (IVF) attempts with good quality embryos. The definition should also take advanced maternal age and embryo stage into consideration.
Asher Bashiri, Katherine Ida Halper, Raoul Orvieto   +2 more
doaj   +1 more source

Influence of laparoscopic surgery for endometriosis and its recurrence on perinatal outcomes

Reproductive Medicine and Biology, 2022
Purpose It is unknown whether surgery for endometriosis or recurrence of endometriosis affects obstetric outcomes. Methods A total of 208 pregnant women with a history of endometriosis were analyzed. Patients who had endometriomas >3 cm and no history of
Yosuke Ono, Kyoko Furumura, Osamu Yoshino, Hajime Ota, Yasushi Sasaki, Takao Hidaka, Yoshiyuki Fukushi, Shuji Hirata, Hideto Yamada, Shinichiro Wada   +9 more
doaj   +1 more source

Nitric Oxide Donor Administration For improvement of Uterine Blood Flow in Unexplained Recurrent Pregnancy Loss [PDF]

International Journal of Medical Arts, 2021
Background: Recurrent pregnancy loss is still a challenging obstetric condition.  It linked to impaired uterine blood, and vasodilators seem to prevent recurrent pregnancy loss.
Mazen A. El-Zahry
doaj   +1 more source

Pregnancy loss and risk of multiple sclerosis and autoimmune neurological disorder: A nationwide cohort study.

PLoS ONE, 2022
BackgroundThe loss of one or more pregnancies before viability (i.e. pregnancy loss or miscarriage), has been linked to an increased risk of diseases later in life such as myocardial infarction and stroke. Recurrent pregnancy loss (i.e. three consecutive
Anders Pretzmann Mikkelsen, Pia Egerup, Astrid Marie Kolte, David Westergaard, Henriette Svarre Nielsen, Øjvind Lidegaard   +5 more
doaj   +1 more source

Chronic Infection in Recurrent Pregnancy Loss

Fertility & Reproduction, 2023
In the present study, the effects of chronic endometritis (CE) on implantation and pregnancy outcomes, the effects of CE on endometrial function, and the effects of progesterone as a treatment for CE were examined.
Fuminori Kimura
doaj   +1 more source

Recurrent pregnancy loss

Van Tıp Dergisi, 2017
Recurrent loss of pregnancy (RLP), consecutive loss of three pregnancies before 20 week of pregnancy. Multifactorial causes play a role in etiology. However, in many cases a definite reason can not be established.
Şerif Aksin
doaj   +1 more source

Oxidative/nitrosative stress increased the risk of recurrent pregnancy loss–Taiwan Recurrent Pregnancy Loss and Environmental Study (TREPLES)

Redox Biology, 2023
Objective: Oxidative stress biomarkers (OSBs) may be strongly associated with disease progression and recurrent pregnancy loss (RPL). However, the research on associations of most OSBs (e.g., 8-nitroguanine [8-NO2Gua] and 4-hydroxy-2-nonenal-mercapturic ...
Yu-Jung Lin, Wei-Hsiang Chang, Pao-Lin Kuo, Hsin-Chang Chen, Wan-Ting Chang, Po-Chin Huang   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source