Results 61 to 70 of about 1,995,629 (215)

Recurrent and Sustained Viral Infections in Primary Immunodeficiencies

Frontiers in Immunology, 2017
Viral infections are commonplace and often innocuous. Nevertheless, within the population of patients with primary immunodeficiencies (PIDDs), viral infections can be the feature that drives a diagnostic evaluation or can be the most significant ...
Melanie A. Ruffner, Kathleen E. Sullivan, Sarah E. Henrickson   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

FREQUENTLY ILL CHILDREN: WHAT ELSE BESIDES INFECTIONS?

Вопросы современной педиатрии, 2013
An original concept of differential diagnostics of various conditions, referred by practitioners as «frequently ill children», is shown in this article, which represents a literature review and the authors’ own data.
D. Yu. Ovsyannikov, T. Yu. Illarionova, L. V. Pushko, L. G. Kuz'menko   +3 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

RECURRENT RESPIRATORY INFECTIONS IN CHILDREN

Children's medicine of the North-West
В лекции представлены анатомо-физиологические предпосылки возникновения, этиопатогенетические механизмы и медико-социальные факторы риска формирования рекуррентной респираторной патологии у детей разного возраста. Описаны возможности профилактики хронических заболеваний и реабилитационных мероприятий у детей с рекуррентными респираторными инфекциями.
A. V. Permyakova, N. S. Pospelova, K. S. Korotaeva, I. E. Berber   +3 more
openaire   +2 more sources

Case report: Mounier-Kuhn syndrome

Indian Journal of Radiology and Imaging, 2008
Tracheobronchomegaly or Mounier-Kuhn syndrome is a rare disorder characterized by marked dilatation of the trachea and main bronchi, bronchiectasis, and recurrent respiratory tract infections.
Satish Kachhawa, M Meena, Gaurav Jindal, Bharat Jain   +3 more
doaj   +1 more source

Association of recurrent upper respiratory tract infections with low production of oxygen intermediates in children

Jornal de Pediatria, 2022
Objectives: Upper respiratory tract infections in children generally have significant morbidity and mortality. There is little data available about functional immaturity of the immune system and the child's susceptibility to infections at the beginning ...
Natália Vieira Inácio Calapodopulos, Mônica Miguel Sawan-Mendonça, Marcos Vinicius da Silva, Carlo Jose Freire Oliveira, Virgínia Resende Weffort, Denise Bertululucci Rocha Rodrigues, Virmondes Rodrigues Jr   +6 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Mycoplasma pneumoniae carriage in children with recurrent respiratory tract infections is associated with a less diverse and altered microbiotaResearch in context

EBioMedicine, 2023
Summary: Background: Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in school-aged children and can be preceded by asymptomatic carriage. However, its role in recurrent respiratory tract infections is unclear.
Mischa H. Koenen, Ruben C.A. de Groot, Wouter A.A. de Steenhuijsen Piters, Mei Ling J.N. Chu, Kayleigh Arp, Raïza Hasrat, Ad C.J.M. de Bruijn, Silvia C. Estevão, Erhard van der Vries, Jeroen D. Langereis, Marianne Boes, Debby Bogaert, Annemarie M.C. van Rossum, Wendy W.J. Unger, Lilly M. Verhagen   +14 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source