Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
CT angiography-derived plaque and perivascular fat radiomics for predicting ipsilateral stroke recurrence in patients with carotid atherosclerosis. [PDF]
Wei J +8 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Salvage of locoregionally recurrent head and neck cancer: an NRG oncology working group review. [PDF]
Ward MC +10 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Accelerated development of rice near-isogenic lines based on rapid generation advance (RGA) and target capture sequencing (TCS). [PDF]
Jeong SK +9 more
europepmc +1 more source
Functional Interpretation of Recurrent Genetic Variants in Hepatocellular Carcinoma: Molecular Consequences and Clinical Relevance. [PDF]
Ye Y +5 more
europepmc +1 more source
The Extrachromosomal DNA Fusion Factory: Extrachromosomal Genesis of Oncogenic Fusion Transcripts. [PDF]
Maimaitiyiming Y +2 more
europepmc +1 more source
Spatiotemporal Fusion for Stock Prediction via Hypergraph Attention Gated Recurrent Units. [PDF]
Cao X, Qian C, Huang H.
europepmc +1 more source
Whole-genome characteristics of isolates from recurrent <i>Clostridioides difficile</i> infections. [PDF]
Zheng L +6 more
europepmc +1 more source

