Results 51 to 60 of about 21,415 (301)

Characterisation of recycled aggregate concrete through x-ray mapping

, 2016
Every year, urban development generates large volumes of solid waste due to the construction and demolition. Most of the waste from construction becomes landfilled; however, as the population grows continuously, land demand soon becomes a shortage ...
Huang, Qingtao (S33004), Murphy, Timothy D. (S30071), Wuhrer, Richard (R17216), Tan, Ee Loon (R14425)   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Influência das propriedades físicas de agregados reciclados sobre a retração por secagem em concreto auto-adensável [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Civil, Florianópolis, 2009Embora a utilização de materiais secundários, ou subprodutos, venha ganhando espaço no desenvolvimento ...
Perius, Gustavo Rodolfo
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

THE PERFORMANCE OF CONCRETE CONTAINING HIGH VOLUMES OF RECYCLED MATERIALS FOR USE IN PAVEMENT APPLICATIONS [PDF]

, 2017
America’s roadway system is in need of a more sustainable, efficient, and innovative plan to improve the condition if its infrastructure. As a possible solution, this research focuses on using recycled concrete aggregate and waste by-products to not only
Allen, Lexis D.
core  

Influence of Recycled Aggregate on Physical and Mechanical Properties of High Performance Recycled Aggregate Concrete

, 2011
Influence of recycled aggregate on slump, compressive strength and chloride ion permeability of recycled aggregate concrete was investigated. As is shown by the results, although recycled aggregate belongs to the category of poor quality aggregate, the ...
Jia Ying Sun, Yi Dong Xu
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Investigation on the properties of concrete with recycled polyethylene terephthalate (PET) granules as fine aggregate replacement [PDF]

, 2022
Waste management is an area of significant global concern. The reuse of waste materials (such as: plastics, glass, wood, etc.) in concrete manufacturing has been studied for potential cost savings, improvements in quality, and reduction of environmental ...
Lokuge, Weena, Eyni Kangavar, Mohammad, Kangavar, Mohammad Eyni, Manalo, Allan, Frigione, Mariaenrica, Karunasena, Warna   +5 more
core   +1 more source