Results 61 to 70 of about 21,415 (301)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Influência da substituição do agregado miúdo natural por agregado reciclado fino em propriedades de argamassas e concretos [PDF]

open access: yes, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia CivilA reciclagem de resíduos de construção e demolição (RCD) tem-se mostrado uma boa alternativa na redução do impacto causado ...
Pedrozo, Ruben Francisco Esteche
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Shear capacity modeling for I- and H-shaped steel reinforced recycled aggregate concrete beams: A short communication study based on modified compression field theory [PDF]

open access: yesAIP Advances
Against the backdrop of resource recycling of construction and demolition waste, the existing calculation methods for shear capacity of steel reinforced recycled aggregate concrete beams in engineering applications fail to fully account for the ...
Ruoqian Zhang   +5 more
doaj   +1 more source

New Trends in Recycled Aggregate Concrete

open access: yes, 2019
This book is the result of a Special Issue published in Applied Sciences, entitled “New Trends in Recycled Aggregate Concrete"". It identifies emerging research areas within the field of recycled aggregate concrete and contributes to the increased use of
de Brito, Jorge   +2 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Study on Performance of Recycled Aggregate Concrete

open access: yes, 2011
The properties of recycled coarse aggregate and the slump, the physical and mechanical properties and durability of recycled aggregate concrete were studied through tests.
Shao Wei Yao   +2 more
core   +1 more source

Fatigue limit of recycled aggregate concrete [PDF]

open access: yes, 2014
This paper presents the main results of the research carried out to obtain the fatigue limit of concrete incorporating recycled aggregate from concrete.
Thomas García, Carlos   +4 more
core   +1 more source

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

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