Results 71 to 80 of about 224,513 (244)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Investigations on the Solubility of Vortioxetine Based on X-ray Structural Data and Crystal Contacts
Crystals, 2019 Investigation on the solid-state pharmaceutical chemistry has been known as an intriguing strategy to not only modify the physicochemical properties of drugs but also expand the solid form landscape.
Xian-Rui Zhang +3 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
Dynamic Recrystallization and Microstructural Evolution During Hot Deformation of Al-Cu-Mg Alloy
MetalsIsothermal hot compression tests were performed on an Al-4.8Cu-0.25Mg-0.32Mn-0.17Si alloy using a Gleeble-3500 thermomechanical simulator within the temperature range of 350–510 °C and strain rate range of 0.001–10 s−1, achieving a true strain of 0.9 ...
Fangyan He +10 more
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
Metals, 2017 Aluminum ultra-purification is commonly realized through a combination of three-layer electrolytic refining and fractional crystallization, mostly using zone melting.
Danilo C. Curtolo +4 more
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, 1993 In this paper we improve a model checking algorithm based on the tableau method of Stifling and Walker. The algorithm proves whether a property expressed in the modal mu-calculus holds for a state in a finite transition system. It makes subsequent use of subtableaux which were calculated earlier in the proof run.
openaire +2 more sources
Advanced Engineering Materials, EarlyView.This article demonstrates the successful qualification of a copper–tungsten composite for laser powder bed fusion. The resulting components exhibited high density, high thermal conductivity, and reduced thermal expansion. Heat sinks with complex geometries were successfully manufactured, clearly showcasing the material's potential for additive ...
Simon Rauh +6 more
wiley +1 more source
Journal of Thermal Science and Technology, 2013 We present the numerical simulation, using the finite difference time domain (FDTD) method, of the radiative heat transfer between two thin SiC slabs. We aim to explore the ability of the FDTD method to reproduce the analytical results for the Surface ...
Alejandro DATAS +2 more
doaj +1 more source