Results 71 to 80 of about 381,548 (294)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Performance of Stainless-Steel Bipolar Plates (SS-BPPs) in Polymer Electrolyte Membrane Water Electrolyser (PEMWE): A Comprehensive Review

open access: yesCompounds
Bipolar Plates (BPPs) play a critical role in Polymer Electrolyte Membrane Water Electrolysers (PEMWEs) for effective hydrogen generation. The performance and longevity of the system can be considerably impacted by choosing the suitable material for ...
Eirini Zagoraiou   +4 more
doaj   +1 more source

Recycling materials, recycling lives

open access: yes, 2017
In this chapter, Lucy Bell subjects the much-vaunted ‘three pillars’ of sustainability to critique via an example not from literary text but from literary production. She discusses the operations of the Latin American editoriales cartoneras publishing houses, where books are handmade from recycled cardboard and often individually produced and sold, as ...
openaire   +2 more sources

Differential Item Functioning on the Patient Health Questionnaire‐8 by Disease Subtype, Language, Sex, and Age among People with Systemic Sclerosis: A Scleroderma Patient‐centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, Accepted Article.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +109 more
wiley   +1 more source

Investigations on the Solubility of Vortioxetine Based on X-ray Structural Data and Crystal Contacts

open access: yesCrystals, 2019
Investigation on the solid-state pharmaceutical chemistry has been known as an intriguing strategy to not only modify the physicochemical properties of drugs but also expand the solid form landscape.
Xian-Rui Zhang   +3 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

open access: yesAdvanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti   +5 more
wiley   +1 more source

Dynamic Recrystallization and Microstructural Evolution During Hot Deformation of Al-Cu-Mg Alloy

open access: yesMetals
Isothermal hot compression tests were performed on an Al-4.8Cu-0.25Mg-0.32Mn-0.17Si alloy using a Gleeble-3500 thermomechanical simulator within the temperature range of 350–510 °C and strain rate range of 0.001–10 s−1, achieving a true strain of 0.9 ...
Fangyan He   +10 more
doaj   +1 more source

Investigating the Effects of Build Height on Mechanical Behavior of Large‐Scale Laser Wire Directed Energy Deposited Nickel Titanium Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
Laser wire directed energy deposition process was leveraged to fabricate large scale NiTi alloy wall. Evaluation of build‐height‐dependent tribo‐mechanical properties revealed significant differences in location specific sample characteristics. The middle region achieved optimal performance (superior wear resistance, balanced strength‐ductility ...
Hyunsuk Choi   +5 more
wiley   +1 more source

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