Results 51 to 60 of about 159,906 (248)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Leaching of rare earth elements from bastnasite ore (second part) / Выщелачивание редкоземельных элементов из пород, содержащих фторкарбонаты – вторая часть / Rastvaranje elemenata retkih zemalja iz ruda koje sadrže fluorokarbonatni mineral - drugi deo [PDF]

open access: yesVojnotehnički Glasnik, 2019
Dissolution of rare earth elements from bastnasite ore was studied using different leaching agents such as sulfuric acid, hydrochloric acid, acetic acid, citric acid and sodium hydroxide at 70°C, with 1mol/L, solid/liquid ratio of 0.05 between 30 and ...
Srećko R. Stopić, Bernd G. Friedrich
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Leaching of rare earth elements with sulfuric acid from bastnasite ores / Выщелачивание редкоземельных металлов серной кислотой из пород, содержащих фторкарбонаты / Rastvaranje elemenata retkih zemalja sumpornom kiselinom iz ruda koje sadrže fluorokarbonatni mineral [PDF]

open access: yesVojnotehnički Glasnik, 2018
Dissolution of rare earth elements from bastnasite ores was studied using sulfuric acid at the atmospheric pressure. The one step strategy with sulfuric acid was studied further and the results showed that filtering difficulties do not happen for the ...
Srećko R. Stopić, Bernd G. Friedrich
doaj   +1 more source

Formation and application of hydrogen in non-ferrous metallurgy

open access: yesVojnotehnički Glasnik, 2023
Introduction/purpose: Hydrogen is the most abundant element in the universe (75 % by mass) and the lightest element (with a density of 0.00082 g/cm3) which consists of only one proton and one electron. Because of its presence in many different forms such
Srećko R. Stopić, Bernd G. Friedrich
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Concentration and Separation of Scandium from Ni Laterite Ore Processing Streams

open access: yesMetals, 2017
The presence of a considerable amount of scandium in lateritic nickel-cobalt ores necessitates the investigation of possible processing alternatives to recover scandium as a byproduct during nickel and cobalt production.
Şerif Kaya   +3 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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