Results 101 to 110 of about 1,018,273 (298)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Use of an Active Canopy Sensor Mounted on an Unmanned Aerial Vehicle to Monitor the Growth and Nitrogen Status of Winter Wheat

Remote Sensing, 2020
Using remote sensing to rapidly acquire large-area crop growth information (e.g., shoot biomass, nitrogen status) is an urgent demand for modern crop production; unmanned aerial vehicle (UAV) acts as an effective monitoring platform.
Jie Jiang, Zeyu Zhang, Qiang Cao, Yan Liang, Brian Krienke, Yongchao Tian, Yan Zhu, Weixing Cao, Xiaojun Liu   +8 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Imaging spectroscopy for bark beetle detection in Norway spruce and the relevance of the red-edge spectral range

International Journal of Applied Earth Observations and Geoinformation
In this study, hyperspectral data of two geographically distant study areas in Germany were analyzed to find the most effective spectral wavelengths for red-edge-based vegetation indices to differentiate bark beetle-infested Norway spruce into three ...
Alexander Marx, Anne Clasen, Johannes May, Simon König, Birgit Kleinschmit, Michael Förster   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Estimating Corn Growth Parameters by Integrating Optical and Synthetic Aperture Radar Features into the Water Cloud Model

Agriculture
Crop growth parameters are the basis for evaluation of crop growth status and crop yield. The aim of this study was to develop a more accurate estimation model for corn growth parameters combined with multispectral vegetation indexes (VIopt) and the ...
Yanyan Wang, Zhaocong Wu, Shanjun Luo, Xinyan Liu, Shuaibing Liu, Xinxin Huang   +5 more
doaj   +1 more source

On the properties of discs around accreting brown dwarfs

, 2010
We present a grid of models of accreting brown dwarf systems with circumstellar discs. The calculations involve a self-consistent solution of both vertical hydrostatic and radiative equilibrium along with a sophisticated treatment of dust sublimation. We
Allen, Allers, Anders, Asplund, Barrado y Navascués, Bertout, Bessell, Bessell, Bessell, Bessell, Bouvier, Bouvier, Bouy, Bryden, Camenzind, Carpenter, Chabrier, Clarke, Cohen, Cohen, Currie, Dahm, Dullemond, Elias, Ercolano, Fukugita, Gatti, Griffin, Griffin, Gullbring, Gutermuth, Haisch, Harries, Harries, Hartmann, Hawarden, Herbst, Herczeg, Holland, Isella, Jayawardhana, Joergens, Johnson, Kama, Kennedy, Kenyon, Koenigl, Kurosawa, Kurosawa, Lada, Lada, Leggett, Lucy, Luhman, Luhman, Luhman, Martín, Mayne, Mayne, Meyer, Mohanty, Mohanty, Monin, Morrow, Muzerolle, Muzerolle, Najita, Nathan J. Mayne, Natta, Natta, Natta, Neugebauer, Noels, Pascucci, Pinte, Poglitsch, Pollack, Rice, Robitaille, Scholz, Scholz, Shakura, Shu, Siess, Siess, Simons, Skrutskie, Stephens, Tannirkulam, Tim J. Harries, Tokunaga, Tout, Walker, White, Wood, Zapatero Osorio   +95 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Vegetation Indices as Rapid, Non‐Destructive Tool to Assess Nitrogen Status in Irrigated Rice

Modern Agriculture
The use of optical radiation sensors is a promising strategy for nitrogen management as it reduces the costs of chemical analyses and allows quick decision‐making in the supplementary application of N to irrigated rice.
Marcos Paulo dos Santos, Nívea Patrícia Ribeiro Reges, Alberto Baêta dos Santos, Luís Fernando Stone, Alexandre Bryan Heinemann   +4 more
doaj   +1 more source