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Frontiers in Cellular and Infection Microbiology, 2023 The gut microbiome is clearly linked to the development of various autoimmune diseases, however, its association with immune thrombocytopenia (ITP) is less well understood. The current study collected 73 samples, including 36 from healthy individuals and
Xue Rui +5 more
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Red Blood Cells: Chasing Interactions [PDF]
Frontiers in Physiology, 2019 Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and most intracellular machineries during their maturation process. RBC are fundamental for the nearly all basic physiologic dynamics and they are key cells in the body's respiratory system by being responsible for the oxygen transport to all cells and tissues ...
Virginia Pretini +8 more
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Health Psychology and Behavioral Medicine, 2022 Objective Sickle cell disease (SCD) is the most frequent monogenic disease worldwide. Psychological and behavioural factors are often reported as playing a significant role in predicting SCD health outcomes.
Damien Oudin Doglioni +3 more
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Malaria Journal, 2020 Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika +4 more
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Towards manufactured red blood cells for the treatment of inherited anemia
Haematologica, 2021 Patients with inherited anemia and hemoglobinopathies (such as sickle cell disease and β-thalassemia) are treated with red blood cell (RBC) transfusions to alleviate their symptoms.
Stephanie Pellegrin +2 more
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Red Blood Cell Magnetophoresis [PDF]
Biophysical Journal, 2003 The existence of unpaired electrons in the four heme groups of deoxy and methemoglobin (metHb) gives these species paramagnetic properties as contrasted to the diamagnetic character of oxyhemoglobin. Based on the measured magnetic moments of hemoglobin and its compounds, and on the relatively high hemoglobin concentration of human erythrocytes, we ...
Zborowski, Maciej +5 more
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Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures
Stem Cell Research & Therapy, 2018 Background Senescent cells are undesirable in cell therapy products due to reduced therapeutic activity and risk of aberrant cellular effects, and methods for assessing senescence are needed. Early-passage mesenchymal stromal cells (MSCs) are known to be
S. Oja +4 more
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Cells, 2022 Oxygen gradient ektacytometry (oxygenscan) measures the changes in red blood cell (RBC) deformability in normoxia and during deoxygenation. We investigated the changes in RBC deformability, measured by both oxygenscan and classical shear-stress-gradient ...
Camille Boisson +12 more
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Journal of Translational Medicine, 2017 Background Red blood cell (RBC) depletion is a standard graft manipulation technique for ABO-incompatible bone marrow (BM) transplants. The BM processing module for Spectra Optia, “BMC”, was previously introduced.
Soo-Zin Kim-Wanner +11 more
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Red blood cell morphology [PDF]
International Journal of Laboratory Hematology, 2013 SummaryThe foundation of laboratory hematologic diagnosis is the complete blood count and review of the peripheral smear. In patients with anemia, the peripheral smear permits interpretation of diagnostically significant red blood cell (RBC) findings. These include assessment of RBC shape, size, color, inclusions, and arrangement.
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