Results 131 to 140 of about 1,224,953 (315)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Overview of the blood transfusion policy in preterms on the Neonatal Intensive Care Unit [PDF]

open access: yes, 2013
Preterm infants on the Neonatal Intensive Care Unit receive a greater number of red cell transfusions than any other hospitalised group. Over the past twenty years research has focused on setting standards to determine when it is necessary to transfuse ...
Attard Montalto, Simon   +4 more
core  

Expression of CD55, CD59, and CD35 on red blood cells of β-thalassaemia patients [PDF]

open access: yes, 2017
Aim of the study : β-thalassaemia (β-Thal) is considered a severe, progressive haemolytic anaemia, which needs regular blood transfusions for life expectancy.
Mustafa Yildiz   +4 more
core   +1 more source

Efficient isolation of highly purified tonsil B lymphocytes using RosetteSep with allogeneic human red blood cells

open access: yesBMC Immunology, 2009
Background Human tonsils are a rich source of B lymphocytes exhibiting a variety of phenotypes and activation states. Existing methods of purification are time consuming or costly.
Deans Julie P   +2 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Blood-mimicking fluid for biotechnological applications. Fluid dynamic behavior of red blood cells and droplets under confined shear flow [PDF]

open access: yes, 2009
In spite of the development of cardio-vascular prosthetic devices, prosthetic heart valves, pulsatile blood pumps, models of the circulatory system, and sophisticated studies of flow through the complex geometries of the circulation, an analog test fluid
GUIDO, STEFANO
core  

Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]

open access: yes, 1990
In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin   +3 more
core   +1 more source

Eficacy and safety of washed red blood cells and white suspended red blood cells in the treatment of autoimmune hemolytic anemia: a meta-analysis

open access: yesZhongguo shuxue zazhi
[Objective] To systematically evaluate the therapeutic effect of washed red blood cells and white suspended red blood cells on patients with autoimmune hemolytic anemia, and to provide reference for their clinical treatment. [Methods] CNKI, Wanfang, VIP,
FU Wenda, WEI Hua, LI Dan, YANG Longfei
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques [PDF]

open access: yes, 2006
So far, little is known about the interaction of nanoparticles with lung cells, the entering of nanoparticles, and their transport through the blood stream to other organs.
Schürch, Samuel   +4 more
core   +1 more source

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