Results 151 to 160 of about 1,821,043 (357)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Lipids of rabbit blood cells. Date for red cells and polymorphonuclear leucocytes [PDF]

, 1950
N. S. Burt, R. J. Rossiter
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

PHAGOCYTOSIS OF RED BLOOD-CELLS AFTER TRANSFUSION [PDF]

, 1910
J. G. Hopkins
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

MEMBRANE EQUILIBRIA AND THE ELECTRIC CHARGE OF RED BLOOD CELLS [PDF]

, 1924
Calvin B. Coulter
openalex   +1 more source

Oscillation dynamics of embolic microspheres in flows with red blood cell suspensions

, 2012
Dynamic nature of particle motion in blood flow is an important determinant of embolization based cancer therapy. Yet, the manner in which the presence of high volume fraction of red blood cells influences the particle dynamics remains unknown.
Anand M., Dario Carugo, Galdi G. P., Schneck D. J., Suman Chakraborty, Tamal Das, Xunli Zhang   +6 more
core   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

ASSOCIATION OF HUMAN NEUTROPHIL ANTIGENS WITH HAPLOTYPES IN SICKLE CELL ANEMIA

Hematology, Transfusion and Cell Therapy
Introduction: The SLC44A2 gene (rs2288094) encodes a choline-like membrane transporter expressed in various cells including blood cells. Genetic variants in this gene are associated with blood antigen polymorphisms, such as the human neutrophil antigens (
JO Rios, CC Lobo, S Azouzi, CR Bonini-Domingos   +3 more
doaj  

Red blood cells: the immune system’s hidden regulator, investigation into the role of red blood cells in inflammatory cytokine signalling [PDF]

, 2016
Red blood cells are the most abundant cell type in mammals, although, they are mostly described as inert carriers of haemoglobin that function only in gas exchange and transport.
Karsten, Elisabeth
core