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Red blood cell “aggregability”
Clinical Hemorheology and Microcirculation, 2009It is well understood that the extent of red blood cell (RBC) aggregation is determined by both plasmatic and cellular factors [10]. It is also clear that alterations of plasmatic and cellular factors may be related to separate disease processes [1]. For example, plasma composition may change (e.g., fibrinogen concentration increase) due to an acute ...
Oguz K, Baskurt, Herbert J, Meiselman
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Clinics in Laboratory Medicine, 2021
Red blood cell (RBC) transfusions are necessary to increase a patient's oxygen carrying capacity. The optimal transfusion trigger remains elusive, but a restrictive transfusion trigger of 7 g/dL has been shown in studies to reduce RBC transfusions without adversely affecting patient outcomes.
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Red blood cell (RBC) transfusions are necessary to increase a patient's oxygen carrying capacity. The optimal transfusion trigger remains elusive, but a restrictive transfusion trigger of 7 g/dL has been shown in studies to reduce RBC transfusions without adversely affecting patient outcomes.
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The International Journal of Biochemistry & Cell Biology, 2002
Red blood cells are derived from haemopoietic stem cells in bone marrow. Following a series of maturation steps, directed largely by the hormone erythropoietin (Epo), red cells enucleate and enter the circulatory system. In circulation these small, flexible biconcave cells containing haemoglobin transport O(2) from the lungs to the periphery, and CO(2)
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Red blood cells are derived from haemopoietic stem cells in bone marrow. Following a series of maturation steps, directed largely by the hormone erythropoietin (Epo), red cells enucleate and enter the circulatory system. In circulation these small, flexible biconcave cells containing haemoglobin transport O(2) from the lungs to the periphery, and CO(2)
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Artificial Cells, Blood Substitutes, and Biotechnology, 1998
Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Cryopreservation of red blood cells
Vox Sanguinis, 1994“There is practically no mention in the literature of attempts to keep red blood cells alive in vitro, yet methods for their preservation might have much practical importance, and certainly would possess theoretical interest. Kept cells could be utilized for serum reactions or for transfusion.
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Survey of Anesthesiology, 1969
AS an essential therapeutic agent in modern medical practice, human blood is clearly a valuable and limited natural resource. The total use of blood grows annually, as does the difficulty of procuring it in amounts sufficient to meet expanding needs.
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AS an essential therapeutic agent in modern medical practice, human blood is clearly a valuable and limited natural resource. The total use of blood grows annually, as does the difficulty of procuring it in amounts sufficient to meet expanding needs.
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Cryopreservation of Red Blood Cells
2018Glycerol and trehalose are widely used protective agents in the cryopreservation of red blood cells (RBCs). This chapter presents a protocol for use of these agents as cryoprotectants of RBCs, with post-thaw assessment of cell survival and cellular oxidative-reductive status. The main aim is to provide a framework for further studies aimed at improving
Noha A S, Al-Otaibi +2 more
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On the Shape of the Red Blood Cells
Journal of Geometry and Symmetry in PhysicszbMATH Open Web Interface contents unavailable due to conflicting licenses.
González, Ramon +2 more
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Transfusion, 1973
A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
G A, Becker, R H, Aster
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A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
G A, Becker, R H, Aster
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The Quality of Red Blood Cells
Immunological Investigations, 1995The evolving practice of medicine has required a number of changes in red cell product manufacture to ensure that the final product is more specifically tailored to the needs of the individual patient. As a result of the increasing concern over the risks of transfusion pharmaceutical standards of manufacture are now applied to blood component ...
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