Results 41 to 50 of about 2,648,431 (354)

Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages

FEBS Open Bio, 2017
Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled liberation of iron. Many efforts have been made to understand heme trafficking inside macrophages,
Inês B. Santarino, Otília V. Vieira
doaj   +1 more source

Drug transport by red blood cells

Frontiers in Physiology, 2023
This review focuses on the role of human red blood cells (RBCs) as drug carriers. First, a general introduction about RBC physiology is provided, followed by the presentation of several cases in which RBCs act as natural carriers of drugs. This is due to
Sara Biagiotti, Elena Perla, Mauro Magnani   +2 more
doaj   +1 more source

Oxidative stress’s impact on red blood cells: Unveiling implications for health and disease

Medicine
Oxidative stress, a condition characterized by an imbalance between reactive oxygen species (ROS) production and the body’s ability to detoxify them, has emerged as a pivotal factor in the pathophysiology of various diseases.
E. Obeagu, M. C. Igwe, G. U. Obeagu
semanticscholar   +1 more source

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease

, 2012
A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid, Wolters, Dirk, Heiß, Christian, Rodriguez Mateos, Ana, Krenz, Thomas, Kuhnle, G. G. C., Cortese-Krott, Miriam M, Rodriguez-Mateos, Ana, Kelm, Malte, Cortese-Knott, Miriam M., Feelisch, Martin, Rodriguez-Mateos, Z, Kroncke, K.-D., Kröncke, Klaus-Dietrich, Sansone, R., Kuhnle, Gunter G. C., Kelm, M., Heiss, C., Krisp, C., Sansone, Roberto, Horn, P., Feelisch, M., Horn, Patrick, Krisp, Christoph, Krenz, T., Hogg, N., Kuhnle, Gunter, Kuhnle, Gunter G.C., Thasian-Sivarajah, S., Thasian-Sivarajah, Sivatharsini, Wolters, D., Cortese-Krott, Miriam M., Hogg, Neil, Cortese-Krott, M. M.   +33 more
core   +1 more source

Endovascular Treatment of Aortic Aneurysms and Blood Transfusion. What do We Need?

Acta Médica Portuguesa, 2016
Introduction: Comparatively to open repair, endovascular aneurysm repair has reduced transfusion rates but there’s no recommendation about number of red blood cells units to be crossmatched preoperatively.
Rui Machado, Luís Loureiro, Inês Antunes, Jorge Coutinho, Rui Almeida   +4 more
doaj   +1 more source

All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD [PDF]

, 2011
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the ...
Smith, Antony, Ian R. MacGregor, Groschup, Martin H., Hunter, N., Hunter, Nora, Prowse, C.V., Tan, B.C., Hornsey, V.S., Boon Chin Tan, Sandra McCutcheon, Jean C Manson, Antony Smith, E. Fiona Houston, Jean C. Manson, Alejo-Blanco, Richard, Manson, J.C., Tan, Boon Chin, Turner Marc, Manson, Jean C., Houston E. Fiona, Alejo Blanco, A.R., Turner, Marc, Groschup Martin H., MacGregor, Ian R., Houston, Fiona, Christopher V Prowse, Turner, M., E Fiona Houston, Alejo Blanco Anthony Richard, Groschup, M.H., Martin H Groschup, Smith Antony, de Wolf, C., Christopher V. Prowse, Hunter Nora, Prowse, Christopher V., Christopher de Wolf, Anthony Richard Alejo Blanco, MacGregor Ian R., de Wolf Christopher, Marc Turner, de Wolf, Christopher, Valerie S. Hornsey, Smith, A., Manson Jean C., Prowse Christopher V., Ian R MacGregor, Prowse, C. V., Hornsey, Valerie S., McCutcheon Sandra, MacGregor, I.R., McCutcheon, Sandra, Nora Hunter, Tan Boon Chin, Hornsey Valerie S., Martin H. Groschup, McCutcheon, S., Houston, E.F., Valerie S Hornsey   +58 more
core   +1 more source

Red blood cells are dynamic reservoirs of cytokines

Scientific Reports, 2018
Red blood cells (RBCs) have been shown to affect immune function and can induce inflammatory responses after transfusion. The transfusion of washed RBCs can significantly reduce adverse effects, however, the soluble factors that may mediate these effects
Elisabeth Karsten, Edmond J. Breen, Benjamin R. Herbert   +2 more
semanticscholar   +1 more source

The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes

, 1975
Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal ...
Shimada, Atsuko
core   +1 more source

SARS-CoV-2 Infection and Anemia—A Focus on RBC Deformability and Membrane Proteomics—Integrated Observational Prospective Study

Microorganisms
Introduction: The multifaceted impact of COVID-19 extends beyond the respiratory system, encompassing intricate interactions with various physiological systems. This study elucidates the potential association between SARS-CoV-2 infection and anemia, with
Angelo D’Alessandro, Elena Krisnevskaya, Valentina Leguizamon, Ines Hernández, Carolina de la Torre, Joan-Josep Bech, Josep-Tomàs Navarro, Joan-Lluis Vives-Corrons   +7 more
doaj   +1 more source

From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals

Frontiers in Physiology, 2017
Erythropoiesis occurs mostly in bone marrow and ends in blood stream. Mature red blood cells are generated from multipotent hematopoietic stem cells, through a complex maturation process involving several morphological changes to produce a highly ...
Martina Moras, S. Lefevre, M. Ostuni
semanticscholar   +1 more source