Results 11 to 20 of about 2,352,522 (319)

Cholesterol Deficiency Causes Impaired Osmotic Stability of Cultured Red Blood Cells

Frontiers in Physiology, 2019
Ex vivo generation of red blood cells (cRBCs) is an attractive tool in basic research and for replacing blood components donated by volunteers. As a prerequisite for the survival of cRBCs during storage as well as in the circulation, the quality of the ...
Claudia Bernecker, Harald Köfeler, Georg Pabst, Martin Trötzmüller, Dagmar Kolb, Dagmar Kolb, Karl Strohmayer, Slave Trajanoski, Gerhard A. Holzapfel, Gerhard A. Holzapfel, Peter Schlenke, Isabel Dorn   +11 more
doaj   +1 more source

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

Malaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika, Alida R. Harahap, Lydia V. Panggalo, Sri Widia A. Jusman, Ari W. Satyagraha   +4 more
doaj   +1 more source

Red Blood Cells: Chasing Interactions [PDF]

Frontiers in Physiology, 2019
Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and most intracellular machineries during their maturation process. RBC are fundamental for the nearly all basic physiologic dynamics and they are key cells in the body's respiratory system by being responsible for the oxygen transport to all cells and tissues ...
Virginia Pretini, Virginia Pretini, Mischa H. Koenen, Lars Kaestner, Lars Kaestner, Marcel H. A. M. Fens, Raymond M. Schiffelers, Marije Bartels, Richard Van Wijk   +8 more
openaire   +5 more sources

Sickle cell disease patients with COVID‐19 in Guadeloupe: Surprisingly favorable outcomes

eJHaem, 2022
We investigate risk factors for hospitalization and difference between sickle cell syndromes in a cohort of COVID‐19 sickle cell disease (SCD) adult patients managed in the Reference Center of Guadeloupe.
Emmanuelle Bernit, Marc Romana, Scylia Alexis‐Fardini, Vanessa Tarer, Pierre‐Marie Roger, Lydia Doumdo, Eléonore Petras, Corine Charneau, Benoit Tressières, Marie Dominique Hardy Dessources, Maryse Etienne‐Julan   +10 more
doaj   +1 more source

Consensus on Complement Inhibitor Therapy and Management of Paroxysmal Nocturnal Hemoglobinuria

罕见病研究
Paroxysmal nocturnal hemoglobinuria (PNH), a rare clonal disease of hematopoietic stem cells caused by mutations in the phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIGA) gene, may lead to the deficiency of glycosylated ...
Red Blood Cell Disease (Anemia) Group, Chinese Society of Hematology, Chinese Medical Association
doaj   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Red cell membrane disorders [PDF]

International Journal of Laboratory Hematology, 2017
AbstractSignificant advances have been made in our understanding of the structural basis for altered cell function in various inherited red cell membrane disorders with reduced red cell survival and resulting hemolytic anemia. The current review summarizes these advances as they relate to defining the molecular and structural basis for disorders ...
J, Narla, N, Mohandas
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Red cell distribution width and mean platelet volume detection in patients with endometrial cancer and endometrial hyperplasia

Health Science Reports
Background Endometrial cancer is the most common malignancy in women in developed countries, and its incidence is increasing annually. Due to the availability and cost‐effectiveness of serum markers of red cell distribution width (RDW), and mean platelet
Zahra Rafiei Sorouri, Roya Kabodmehri, Forozan Milani, Parmoon Parvari   +3 more
doaj   +1 more source

Generation of human induced pluripotent stem cells (CHULAi001-A) from peripheral blood mononuclear cells of a glucose-6-phosphate dehydrogenase (G6PD) deficient subject carrying the Viangchan mutation

Stem Cell Research, 2022
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common genetic enzyme-defect disorder. In this study, CHULAi001-A was established from peripheral blood mononuclear cells of a G6PD-deficient subject who carried the Viangchan variant (871 G > A ...
Malinee Tongbaen, Yasuko Matsumura, Keisuke Okita, Kamonlak Leecharoenkiat   +3 more
doaj   +1 more source