Results 31 to 40 of about 4,116,135 (338)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Investigation of the cytotoxicity of CCVD carbon nanotubes towards human umbilical vein endothelial cells [PDF]

, 2006
The cytotoxicity of different samples of carbon nanotubes synthesised by catalytic chemical vapour deposition was investigated towards human umbilical vein endothelial cells, using two cytotoxicity standard assays (neutral red assay for the cell ...
Baquey, Charles, Bareille, Reine, Durrieu, Marie-Christine, Flahaut, Emmanuel, Remy-Zolghadri, Murielle   +4 more
core   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Blood parameter changes during stopover in a long-distance migratory shorebird, the bar-tailed godwit Limosa lapponica taymyrensis [PDF]

, 2002
Bar-tailed godwits migrate from West African wintering sites to breeding areas in northern Russia with only one stopover. We compared hematocrit (Hct), blood hemoglobin concentration (Hb), and mean cell hemoglobin concentration (MCHb; a measure of the ...
Banerjee, Bergmann, Bordel, Campbell, Campbell, Carmi, Christopher, DeGraw, Drent, Failla, Green, Joop Jukema, Jukema, Landys-Ciannelli, Mairbaurl, Meta M. Landys-Ciannelli, Micozzi, Morton, Piersma, Piersma, Piersma, Reinhart, Riera, Ritchie, Smith, Sokal, Thapliyal, Theunis Piersma, Wingfield, Yen   +29 more
core   +6 more sources

Following red blood cells in a pulmonary capillary [PDF]

, 2007
The red blood cells or erythrocytes are biconcave shaped cells and consist mostly in a membrane delimiting a cytosol with a high concentration in hemoglobin.
B. Maury, B. Sapoval, Benjamin Mauroy, C. Grandmont, J.F. Gerbeau, L. Boudin, Y. Maday   +6 more
core   +2 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Red cell distribution width and mean platelet volume detection in patients with endometrial cancer and endometrial hyperplasia

Health Science Reports
Background Endometrial cancer is the most common malignancy in women in developed countries, and its incidence is increasing annually. Due to the availability and cost‐effectiveness of serum markers of red cell distribution width (RDW), and mean platelet
Zahra Rafiei Sorouri, Roya Kabodmehri, Forozan Milani, Parmoon Parvari   +3 more
doaj   +1 more source

pH regulatory Na/H exchange by Amphiuma red blood cells. [PDF]

, 1994
In Amphiuma red blood cells, the Na/H exchanger has been shown to play a central role in the regulation of cell volume following cell shrinkage (Cala, P. M. 1980. Journal of General Physiology.
Cala, PM, Maldonado, HM
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Energy Dissipation in the Human Red Cell Membrane

Biomolecules, 2023
The membrane of the human red cell consists of a lipid bilayer and a so-called membrane skeleton attached on the cytoplasmic side of the bilayer. Upon the deformation of red cells, energy is dissipated in their cytoplasm and their membrane.
Thomas M. Fischer
doaj   +1 more source