Results 131 to 140 of about 1,925,617 (316)

The arithmetic of arithmetic Coxeter groups

open access: yes, 2018
In the 1990s, J.H. Conway published a combinatorial-geometric method for analyzing integer-valued binary quadratic forms (BQFs). Using a visualization he named the "topograph," Conway revisited the reduction of BQFs and the solution of quadratic ...
Milea, Suzana   +2 more
core   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Target Selection for the SDSS-IV APOGEE-2 Survey

open access: yes, 2017
APOGEE-2 is a high-resolution, near-infrared spectroscopic survey observing roughly 300,000 stars across the entire sky. It is the successor to APOGEE and is part of the Sloan Digital Sky Survey IV (SDSS-IV).
Andrews, B.   +36 more
core   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

The red flags of ulnar neuropathy in leprosy

open access: yesPLoS ONE, 2021
The diagnosis of pure neural leprosy is more challenging because patients share characteristics with other common pathologies, such as ulnar compression, which should be taken into consideration for differential diagnosis.
Márcia Jardim   +7 more
doaj  

The VMC Survey - VI. Quasars behind the Magellanic system

open access: yes, 2012
The number and spatial distribution of confirmed quasi-stellar objects (QSOs) behind the Magellanic system is limited. This undermines their use as astrometric reference objects for different types of studies.
Alcock   +84 more
core   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

Comprehension of coping attitudes and red flags of low back pain by students of the first and seventh semesters of health courses

open access: yesBrJP
BACKGROUND AND OBJECTIVES: Low back pain is a common complaint among the world’s population. Students in the health sector are susceptible to it due to their routines with a heavy study load.
Gabriel Bezerra Pereira   +5 more
doaj   +1 more source

The organization of anticorruption: Getting incentives right! [PDF]

open access: yes
Governments and private firms try to contain corruption among their staff mostly in a top-down, rules-based approach. They limit discretion, increase monitoring or impose harsher penalties.
Graf Lambsdorff, Johann
core  

Determination of Priorities for Footway Reconstruction [PDF]

open access: yes, 1990
This report describes a study conducted for Sheffield City Council to obtain pedestriansr reactions to the quality and acceptability of footways of different construction in different conditions, and to assess pedestriansr preferences for different ...
Leake, G.R., May, A.D., Parry, T.
core  

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