Results 21 to 30 of about 699,548 (260)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Foxes and food subsidies: anthropogenic food use by red and Arctic foxes, and effects on Arctic fox survival, on the Arctic Coastal Plain of Alaska [PDF]

, 2013
Thesis (M.S.) University of Alaska Fairbanks, 2013Food subsidies have the potential to impact wildlife on the Arctic Coastal Plain of Alaska. Red foxes (Vulpes vulpes (L., 1758)) expanded their range into Arctic regions during the 20th century, and the ...
Savory, Garrett
core  

A stochastic model of Echinococcus multilocularis focusing on protoscoleces [PDF]

, 2006
The red fox (Vulpes vulepes) and the vole ( Clethrionomys refocanus) are principal hosts of Echinococcus multilocularis in Hokkaido, Japan. How protoscoleces increases in voles and the level of immunity in foxes remain unknown because of the lack of ...
Fujita, Kazutoshi, Ishikawa, Hirofumi, Nishina, Tomohiko, Tian Tian, Chen   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Analysis of Arkansas Fur Harvest Records - 1942-1984: II. Species Accounts [PDF]

, 1985
Fur harvest records were maintained by the Arkansas Game and Fish Commission on the following 16 furbearers: badger, beaver, bobcat, eastern spotted skunk (civet), coyote, gray fox, long-tailed weasel, mink, muskrat, nutria, opossum, raccoon, red fox ...
Clark, Joseph D., Heidt, Gary A., Peck, James H., Sheldon, Tiny   +3 more
core   +2 more sources

Assessing anti-rabies baiting – what happens on the ground? [PDF]

, 2004
Background Rabies is one of the most hazardous zoonoses in the world. Oral mass vaccination has developed into the most effective management method to control fox rabies. The future need to control the disease in large countries (i.e.
Hans-Hermann Thulke, Thomas Selhorst, Thomas Müller, Tomasz Wyszomirski, Uli Müller, Urs Breitenmoser, K Stöhr, A Vos, A Wandeler, WG Winkler, DH Johnston, DH Johnston, J Barrat, CD MacInnes, CD MacInnes, T Müller, SB Linhart, U Breitenmoser, MI Meltzer, JW Frost, WJ Trewhella, F Cliquet, D Schenzle, T Müller, B Brochier, E Masson, PP Pastoret, U Schaarschmidt, DH Johnston, A Okabe, T Czaran, K Bögel, F Steck, H Schlüter, CE Rupprecht, PJS Fleming, LG Schneider, CA Marks, T Müller, ED Ables, AB Sargeant, HG Lloyd, DR Voigt, TAM Kaphegyi, G Bohrer, F Hansen, PJ Baker, L Tischendorf, A Vos, U Wilhelm, T Selhorst, H-H Thulke, DW Macdonald, FJJ Niewold, WJ Trewhella, M Artois, CA Adkins, J Goszczynski, S Harris, DW Macdonald, BJ Coman, P Cavallini, JS Meia, PD Meek, CPJ Robertson, T Selhorst, M Ahrens, RR Tinline, A Vos   +68 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dental Anomalies in Two Species of Canids: Red Fox (Vulpes Vulpes) and Gray Fox (Urocyon Cinereoargenteus) [PDF]

, 2004
Samples of 510 gray fox and 150 red fox from southern Illinois were examined for the presence of congenital dental abnormalities. Anomalies were found in 177 gray fox (34.7%) and 25 red fox (16.6%).
Gisburne, Teresa
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Diet composition of red fox during rearing in a moor: a case study [PDF]

, 2005
The diet of red fox (Vulpes vulpes) cubs living in a moor in Hungary was studied by scat analysis (n = 77) during the rearing period. The main food source of foxes consisted of small mammals (preferred Microtus voles) which was supplemented with brown ...
Lanszki, József
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