Results 41 to 50 of about 70,615 (259)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Space Use of an Expanding Generalist Predator Is Shaped by Human, Marine and Seasonal Effects on Arctic Tundra

Ecology and Evolution
Generalist species that benefit from human impacts on terrestrial ecosystems and expand their distribution range can threaten biodiversity by outcompeting or predating on native specialists.
Stijn P. Hofhuis, Arnaud Tarroux, Rolf A. Ims, Dorothee Ehrich   +3 more
doaj   +1 more source

Comparative craniometric measurements of two sympatric species of Vulpes in Ikh Nart Nature Reserve, Mongolia [PDF]

Mongolian Journal of Biological Sciences, 2018
In Mongolia, both the red fox (Vulpes vulpes) and corsac fox (Vulpes corsac) occupy broad sympatric ranges, but despite their expansive ranges, few published details of the craniometry of either species exist in Mongolia and other parts of northern and ...
Tserendorj Munkhzul, Richard P. Reading, Bayarbaatar Buuveibaatar, James D. Murdoch   +3 more
doaj   +1 more source

Pearsonema plica in red foxes (Vulpes vulpes) from semi-arid areas of the Iberian Peninsula

International Journal for Parasitology: Parasites and Wildlife, 2022
The nematode Pearsonema plica is a parasite infecting the urinary bladder of carnivores, with a described prevalence ranging from 1 to 90%. This parasite needs earthworms as intermediate host to complete its life cycle, being the red fox (Vulpes vulpes ...
I. Arcenillas-Hernández, M.R. Ruiz de Ybáñez, P. Tizzani, P. Pérez-Cutillas, C. Martínez-Carrasco   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Describing Diet of Imperiled Sierra Nevada Red Foxes and a Carnivoran Competitor Using DNA Metabarcoding

Ecology and Evolution
Montane red foxes (Vulpes vulpes ssp.) native to western North America are of broad conservation interest, occupying a narrow ecological niche and typically restricted to small, isolated populations.
Matthew S. Delheimer, Marie E. Martin, Jennifer Hartman, Katie M. Moriarty, Jennifer M. Allen, Taal Levi   +5 more
doaj   +1 more source

Lipids of the anal sac secretions of the red fox, Vulpes vulpes and of the lion, Panthera leo

Journal of Lipid Research, 1977
Lion anal sac secretion were found to be richer in lipids and to contain more complex less uniform mixtures of lower moleculas weight lipids then the anal sac of the red fox.
E S Albone, T O Grönnerberg
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Multidimensional niche advantages reveal how the red fox stands out in mesopredator release within terrestrial island habitats

Global Ecology and Conservation
Global pressures such as climate change and habitat fragmentation have altered apex predator population sizes, spatial distributions, and trophic interactions.
Junda Chen, Zhirong Zhang, Meichen Yu, Yun Su, Rui Dai, Meiling Zhan, Xu Zhang, Hao Xu, Qi Wei, Wenyu Fan, Liwei Teng, Zhensheng Liu   +11 more
doaj   +1 more source