Results 71 to 80 of about 4,708,890 (355)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A Study on the Impact of Blue Light and Its Brightness on Long-Term Memory

Applied Sciences
The purpose of this study is to evaluate the effect of blue light and its brightness on long-term memory. Blue light was tested under four distinct illuminance conditions ranging from 400 to 1000 lux, and the results were compared with those of red light
Jin-Ho Kim, Kee-Sun Lee, Joung-Myo Shim, Chung-Won Lee   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

New results on long secondary periods in red giants [PDF]

, 2009
Original article can be found at: http://proceedings.aip.org/ Copyright 2009 American Institute of Physics. DOI: 10.1063/1.3246422 [Full text of this paper is not available in the UHRA]Approximately 30% of variable red giants have light curves which show
C. P. Nicholls, I. Soszyński, Joyce Ann Guzik, M.-R. L. Cioni, P. R. Wood, Paul A. Bradley   +5 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Host galaxy colour gradients and accretion disc obscuration in AEGIS z~1 X-ray-selected active galactic nuclei

, 2010
We describe the effect of AGN light on host galaxy optical and UV-optical colours, as determined from X-ray-selected AGN host galaxies at z~1, and compare the AGN host galaxy colours to those of a control sample matched to the AGN sample in both redshift
A. L. Coil, Aird, Baldry, Baldwin, Barger, Barger, Barmby, Bell, Bell, Bell, Bower, Bruzual, Bundy, Bundy, C. M. Pierce, C. N. A. Willmer, Cattaneo, Ciliegi, Ciotti, Coil, Condon, Conselice, Croton, D. J. V. Rosario, Davis, Davis, Dekel, Donley, Drake, E. S. Laird, Faber, Fang, Fasano, Gehrels, Georgakakis, Georgakakis, Georgakakis, Georgakakis, Georgakakis, Gerke, Granato, Grogin, Grogin, Hatziminaoglou, Hopkins, Hopkins, Hopkins, Hopkins, Hopkins, Huang, Ivison, J. M. Lotz, J. R. Primack, Jeltema, K. Bundy, Kassin, Kauffmann, Kauffmann, Kennicutt, Kinney, Konidaris, Koo, Lacy, Laird, Laird, Le Floc'h, Lin, Martin, Martin, Moustakas, Nandra, Nandra, Nandra, Noeske, Noeske, Park, Peterson, Pierce, Pierce, Rigby, Rovilos, S. M. Faber, S. Salim, Salim, Salim, Salim, Sato, Scannapieco, Schawinski, Schiminovich, Silk, Silverman, Silverman, Stern, Symeonidis, Sánchez, Teng, Weiner, Weiner, Willmer, Wilson, Wyder, Yan   +102 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Gravitational red-shift and deflection of slow light [PDF]

, 2008
We explore the nature of the classical propagation of light through media with strong frequency-dependent dispersion in the presence of a gravitational field.
A. N. Jordan, J. B. Hartle, J. C. Howell, J. Dressel, L. D. Landau, L. M. Barkov, M. Born, M. Göckeler, P. W. Milonni, S. G. Rajeev   +9 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

System for producing chroma signals [PDF]

, 1977
A method for obtaining electronic chroma signals with a single scanning-type image device is described. A color multiplexed light signal is produced using an arrangement of dichroic filter stripes.
Lipoma, P. C., Vorhaben, K. H.
core   +1 more source