Results 61 to 70 of about 8,580 (242)

The European palaeoecological record of Swedish red-listed beetles [PDF]

, 2021
Recent global changes have triggered a biodiversity crisis. However, climate fluctuations have always influenced biodiversity and humans have affected species distributions since prehistoric times.
Lemdahl, Geoffrey,, Pilotto, Francesca,, Dynesius, Mats,, Buckland, Philip I., Buckland, Paul C., Lemdahl, Geoffrey, Buckland, Paul C.,, Pilotto, Francesca, Dynesius, Mats, Buckland, Philip I.,   +9 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Occurrence dataset of protected fungal species for the Red Data Book in Yugra Region, Western Siberia [PDF]

Biodiversity Data Journal
The data paper describes a dataset of occurrences of fungal species listed in the Red Data Book of Yugra Region (Western Siberia, Russia). The dataset is based on all digitised records of fungal occurrences in the region.
Nina Filippova, Elena Zvyagina, Sergey Bolshakov, Stanislav Arefyev, Tatiana Bulyonkova, Ilya Filippov, Yury Rebriev, Anton Shiryaev, Iraida Stavishenko, Tatyana Svetasheva   +9 more
doaj   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

NEW RECORDS AND UPDATE LIST SPECIES OF TURTLES IN PU LUONG NATURE RESERVE, THANH HOA PROVINCE

Tạp chí Khoa học
The paper provides morphological data of three turtle species: Black-breasted Leaf Turtle Geoemyda spengleri (Gmélin, 1789), Impressed Turtle Manouria impressa (Günther, 1882), and Big-headed Turtle Platysternon megacephalum Gray, 1831, which were ...
Dau Quang Vinh*, Do Thi Ly, Ha Thi Thao, Le Thi Quynh, Ha Thi Thao, Le Thi Thu Phuong, Le Dinh Phuong   +1 more
doaj   +1 more source

Forests regenerating after clear-cutting function as habitat for bryophyte and lichen species of conservation concern. [PDF]

PLoS ONE, 2011
The majority of managed forests in Fennoscandia are younger than 70 years old but yet little is known about their potential to host rare and threatened species.
Jörgen Rudolphi, Lena Gustafsson
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Forest indicator species correlate only weakly with richness of red-listed species and perform poorly compared to simple stand variables

, 2018
In the face of worldwide biodiversity declines, a variety of conservation measures are being implemented to preserve species and their habitats. Due to imperfect ecological knowledge and limited economic resources, these conservation measures often ...
Olsson, Jörgen, Jean-Michel Roberge, Roberge, Jean-Michel, Therese Lövroth, Jörgen Olsson, Jörgen Rudolphi, Mats Dynesius, Rudolphi, Jörgen, Hjältén, Joakim, Lövroth, Therese, Dynesius, Mats, Joakim Hjältén   +11 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source