Results 81 to 90 of about 404,578 (305)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Construcción de una red neuronal para la simulación de la remoción de cromo hexavalente empleando carbón activado como adsorbente [PDF]

, 2018
Se presenta el desarrollo de un modelo de red neuronal artificial como solución alternativa a la simulación de un proceso de adsorción. Para los ensayos de laboratorio se eligió el cromo hexavalente como contaminante y el carbón activado como material ...
de Celis, Jorge Pablo, Pellegrini, Jorge, Aphesteguy, Juan   +2 more
core  

Reconocimiento de gestos manuales mediante red neuronal artificial [PDF]

, 2020
Las redes neuronales artificiales forman parte del conjunto de tecnologías que conocemos como Inteligencia Artificial y que, hoy en día, son usadas en infinidad de aplicaciones y además poseen un gran potencial de cara al futuro.
San Martín Garaluce, Jon
core   +2 more sources

Enfoque de aprendizaje híbrido evolutivo para redes neuronales en la clasificación de casos médicos

Programación Matemática y Software, 2017
La inteligencia artificial ha ayudado a diversas áreas médicas como lo es el campo del diagnóstico médico, en el que ha servido como un apoyo al profesional de la salud para emitir un diagnóstico.
Erick Estrada Patiño, Guadalupe Castilla Valdez, Juan Frausto Solís, Jesús David Terán Villanueva   +3 more
doaj  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Desempeño de redes neuronales frente a algoritmo ad hoc para segmentación de estructuras.

Revista Iberoamericana de Automática e Informática Industrial RIAI
La necesidad de inspección y mantenimiento en estructuras reticulares metálicas como puentes o torres de alta tensión expone a los operarios humanos a riesgos considerablemente elevados, como caídas desde gran altura y electrocuciones.
Francisco J. Soler, Adrian Peidro, Marc Fabregat-Jaen, Luis Paya, Oscar Reinoso   +4 more
doaj   +1 more source

Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1

Frontiers in Neuroanatomy, 2015
The red nucleus is a neuronal population that plays an important role in forelimb motor control and locomotion. Histologically it is subdivided into two subpopulations, the parvocellular red nucleus located in the diencephalon and the magnocellular red ...
Jesus E. eMartinez-Lopez, Juan A. eMoreno-Bravo, M. Pilar eMadrigal, Salvador eMartinez, Salvador eMartinez, Eduardo ePuelles   +5 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source