Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines [PDF]
Frontiers in Molecular Neuroscience, 2022 Our previous studies have clarified that red nucleus (RN) interleukin (IL)-6 is involved in the maintenance of neuropathic pain and produces a facilitatory effect by activating JAK2/STAT3 and ERK pathways.
Qing-Qing Yang +11 more
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Red Nucleus Excitatory Neurons Initiate Directional Motor Movement in Mice [PDF]
BiomedicinesBackground: The red nucleus (RN) is a phylogenetically conserved structure within the midbrain that is traditionally associated with general motor coordination; however, its specific role in controlling directional movement remains poorly understood ...
Chenzhao He +11 more
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Phylogenetic reduction of the magnocellular red nucleus in primates and inter-subject variability in humans [PDF]
Frontiers in NeuroanatomyIntroductionThe red nucleus is part of the motor system controlling limb movements. While this seems to be a function common in many vertebrates, its organization and circuitry have undergone massive changes during evolution.
Martin Stacho +8 more
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Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3 [PDF]
Journal of Neuroinflammation, 2021 Background Our recent studies have identified that the red nucleus (RN) dual-directionally modulates the development and maintenance of mononeuropathic pain through secreting proinflammatory and anti-inflammatory cytokines.
Hao-Nan Li +10 more
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Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1 [PDF]
Frontiers in Neuroanatomy, 2015 The red nucleus is a neuronal population that plays an important role in forelimb motor control and locomotion. Histologically it is subdivided into two subpopulations, the parvocellular red nucleus located in the diencephalon and the magnocellular red ...
Jesus E. eMartinez-Lopez +5 more
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The human brainstem’s red nucleus was upgraded to support goal-directed action [PDF]
Nature CommunicationsThe red nucleus, a large brainstem structure, coordinates limb movement for locomotion in quadrupedal animals. In humans, its pattern of anatomical connectivity differs from that of quadrupeds, suggesting a different purpose.
Samuel R. Krimmel +25 more
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Constraint-Induced Movement Therapy Promotes Contralesional Red Nucleus Plasticity and Increases Bilateral Motor Cortex-to-Red Nucleus Projections After a Large-Area Stroke [PDF]
Behavioural NeurologyFor decades, scientists have explored the patterns of neural network remodeling that occur after a stroke. Several studies have shown that both motor cortexes (MCs) undergo crucial remodeling after cerebral ischemia.
Peile Liu +6 more
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Hearing in action; auditory properties of neurones in the red nucleus of alert primates [PDF]
Frontiers in Neuroscience, 2014 The response of neurones in the Red Nucleus pars magnocellularis (RNm) to both tone bursts and electrical stimulation were observed in three cynomolgus monkeys (Macaca fascicularis), in a series of studies primarily designed to characterise the influence
Jonathan Murray Lovell +4 more
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Altered innate immune profile in blood of systemic mastocytosis patients
Clinical and Translational Allergy, 2022 Background Mast cells (MC) from systemic mastocytosis (SM) patients release MC mediators that lead to an altered microenvironment with potential consequences on innate immune cells, such as monocytes and dendritic cells (DC).
Alba Pérez‐Pons +16 more
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Frontiers in Neuroanatomy, 2021 The anatomy of the cortical motor system and its relationship to motor repertoire in artiodactyls is for the most part unknown. We studied the origin and termination of the corticospinal tract (CST) and cortico-brainstem projections in domestic pigs ...
Patricia del Cerro +3 more
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