Results 41 to 50 of about 522,391 (291)
Instability of Plastid DNA in the Nuclear Genome
Functional gene transfer from the plastid (chloroplast) and mitochondrial genomes to the nucleus has been an important driving force in eukaryotic evolution.
Timmis, J. +5 more
core +2 more sources
Aim of the study: Parkinson's disease is associated with iron deposition in the brain. The QSM (quantitative susceptibility mapping) is more sensitive than T2-weighted imaging, T2* and R2.
Vahid Shahmaei +4 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Human red nucleus and its surrounding structures.
Upper photomicrographs (A-H) showing distribution of myelinated fiber bundles stained by myelin stain in the human mesodiencephalic structure of successive serial sections. Section A is the most rostral.
T. Philip Hicks (358345) +1 more
core +1 more source
Excitatory rubral cells encode the acquisition of novel complex motor tasks
The red nucleus (RN) is a midbrain nucleus known to be involved in the fine control of limb movements, but its role in motor learning is unclear. Here, the authors identified a neuronal population within the red nucleus, co-expressing Vglut2, PV and ...
Giorgio Rizzi +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Parvicellular red nucleus and its descending tract.
A: Photograph showing points of insertion of DiI crystal into the dorsomedial and ventrolateral parts of the rostral human red nucleus at the level of the fasciculus retroflexus.
T. Philip Hicks (358345) +1 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The diversity and plasticity of descending motor pathways rewired after stroke and trauma in rodents
Descending neural pathways to the spinal cord plays vital roles in motor control. They are often damaged by brain injuries such as stroke and trauma, which lead to severe motor impairments.
Takahiro Inoue, Masaki Ueno
doaj +1 more source
Hypertrophic degeneration of the inferior olivary nucleus impacts perception of gravity
Interruption of the Guillain-Mollaret triangle interconnecting the red nucleus, the inferior olivary nucleus and the contralateral dentate nucleus is predicted to interfere with the dentate nucleus’ role in estimating direction of gravity.
Alexander A Tarnutzer +4 more
doaj +1 more source

