Results 61 to 70 of about 522,391 (291)

Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans [PDF]

, 2010
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2weighted echo planar imaging.
Critchley, Hugo D., R.S.J. Frackowiak (16047230), Frackowiak, R.S.J., McKay, Leanne C., Hugo Critchley (4461955), Frackowiak, R.S., Critchley, H.D., Frackowiak, Richard S J, McKay, L.C., K. Murphy (6727403), Corfield, D.R., Corfield, Douglas R., L.C. McKay (16047227), Corfield, Douglas, D.R. Corfield (16047233), Murphy, K., Murphy, Kevin   +16 more
core   +1 more source

Susceptibility-weighted MR imaging (SWI) of basal ganglia iron deposition in the early and advanced stages of Parkinson's disease

Неврология, нейропсихиатрия, психосоматика, 2019
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease and the first one among the nosological entities of parkinsonism.
A. G. Trufanov, A. A. Yurin, A. B. Buriak, S. A. Sandalov, M. M. Odinak, I. V. Litvinenko   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Facial Motor Nucleus

, 2008
This report contains a summary of expression patterns for genes that are enriched in the facial motor nucleus (VII) of the medulla. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Rachel A. Dalley, Angela L. Guillozet-Bongaarts, Allen Institute for Brain Science, Lydia L. Ng   +3 more
core   +2 more sources

The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics

Frontiers in Neural Circuits
The cerebellar output can trigger whisker movement through indirect projections that pass via several brainstem pre-motor nuclei before reaching the facial nucleus, which directly controls whisker movements in rodents.
Staf Bauer, Peipei Zhai, Nathalie van Wingerden, Hehe Zhao, Vincenzo Romano   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration

, 2010
Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong, Shokouhi, B.N., Lieberman, A.R., Tohyama, K., Wong Bernadette ZY, Campbell, G., Koujiro Tohyama, Anderson Patrick N, Gregor Campbell, Tohyama Koujiro, Campbell Gregor, Samir Siddiqui, Siddiqui, S., Patrick N Anderson, A Robert Lieberman, Bahman N Shokouhi, Wong, B.Z.Y., Shokouhi Bahman N, Anderson, P.N., Lieberman A Robert, Siddiqui Samir   +20 more
core   +1 more source

HISTORICAL RECORD OF A SAUROPOD (DINOSAURIA: TITANOSAURIA) SPECIMEN AT THE MUSEO SEMINARIO VALPARAÍSO: THE FIRST DINOSAUR DISCOVERY OF CHILE?

Publicación Electrónica de la Asociación Paleontológica Argentina
Since its founding in 1870, the Colegio Seminario San Rafael of Valparaíso has offered natural science-related courses, complemented by laboratory work. Thus, in 1881, five science “cabinets” were established within the school premises, and in 1886, the
Omar Vicencio-Campos, Luis Chirino-Gálvez, Jhonatan Alarcón-Muñoz, Antonia Atisha, Agustín G. Martinelli   +4 more
doaj   +1 more source

Progressive supranuclear palsy: new concepts

Arquivos de Neuro-Psiquiatria, 2010
Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia.
Orlando Graziani Povoas Barsottini, André Carvalho Felício, Camila Catherine Henriques de Aquino, José Luiz Pedroso   +3 more
doaj   +1 more source

Carbocyanine dye usage in demarcating boundaries of the aged human red nucleus. [PDF]

PLoS ONE, 2010
BackgroundThough the adult human magnocellular Red nucleus (mNr) is essentially vestigial and its boundaries with neighbouring structures have never been well demarcated, human studies in utero have shown a well developed semilunar mNr wrapping around ...
Satoru Onodera, T Philip Hicks
doaj   +1 more source