Results 71 to 80 of about 970,952 (293)

Carbocyanine dye usage in demarcating boundaries of the aged human red nucleus. [PDF]

PLoS ONE, 2010
BackgroundThough the adult human magnocellular Red nucleus (mNr) is essentially vestigial and its boundaries with neighbouring structures have never been well demarcated, human studies in utero have shown a well developed semilunar mNr wrapping around ...
Satoru Onodera, T Philip Hicks
doaj   +1 more source

Using Hubble Space Telescope Imaging of Nuclear Dust Morphology to Rule Out Bars Fueling Seyfert Nuclei [PDF]

, 1999
If AGN are powered by the accretion of matter onto massive black holes, how does the gas in the host galaxy lose the required angular momentum to approach the black hole?
Alonso-Herrero A., Athanassoula E., Bruzual A., G., John S. Mulchaey, Kormendy J., Kotilainen J. K., Laine S., McLeod K. K., Michael W. Regan, Mirabel I. F.   +9 more
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

HISTORICAL RECORD OF A SAUROPOD (DINOSAURIA: TITANOSAURIA) SPECIMEN AT THE MUSEO SEMINARIO VALPARAÍSO: THE FIRST DINOSAUR DISCOVERY OF CHILE?

Publicación Electrónica de la Asociación Paleontológica Argentina
Since its founding in 1870, the Colegio Seminario San Rafael of Valparaíso has offered natural science-related courses, complemented by laboratory work. Thus, in 1881, five science “cabinets” were established within the school premises, and in 1886, the
Omar Vicencio-Campos, Luis Chirino-Gálvez, Jhonatan Alarcón-Muñoz, Antonia Atisha, Agustín G. Martinelli   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Collateralization of cerebellar output to functionally distinct brainstem areas. A retrograde, non-fluorescent tracing study in the rat

Frontiers in Systems Neuroscience, 2014
The organization of the cerebellum is characterized by a number of longitudinally organized connection patterns that consist of matching olivo-cortico-nuclear zones.
Tom J.H. Ruigrok, Thea M. Teune
doaj   +1 more source

Accreted versus In Situ Milky Way Globular Clusters [PDF]

, 2010
Here we examine the Milky Way's GC system to estimate the fraction of accreted versus in situ formed GCs. We first assemble a high quality database of ages and metallicities for 93 Milky Way GCs from literature deep colour-magnitude data.
Abadi, Allen, Allen, Bekki, Bekki, Bekki, Bellazzini, Bellazzini, Bellazzini, Bellazzini, Bellazzini, Bullock, Burkert, Carollo, Carraro, Carraro, Carraro, Carrera, Carrera, Carretta, Catelan, Coleman, Côté, de Angeli, Dinescu, Dinescu, Dinescu, Dotter, Dotter, Duffau, Duncan A. Forbes, Durrell, Fellhauer, Font, Forbes, Forbes, Frinchaboy, Fusi Pecci, Glatt, Grillmair, Harris, Helmi, Helmi, Helmi, Ibata, Koposov, Lanfranchi, Lauchner, Law, Layden, Lee, Lee, Lin, Lynden-Bell, Mackey, Mackey, Mackey, Martin, Marín-Franch, Mateu, Mayer, Mayer, McConnachie, Minniti, Newberg, Newberg, Norris, Peñarrubia, Peñarrubia, Piotto, Pritzl, Salaris, Searle, Siegel, Spitler, Terry Bridges, Unavane, van den Bergh, van den Bergh, Willett, Zolotov   +80 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Simulation of neutron production in hadron-nucleus and nucleus-nucleus interactions in Geant4 [PDF]

, 2018
Studying experimental data obtained at ITEP [1] on neutron production in interactions of protons with various nuclei in the energy range from 747 MeV up to 8.1 GeV, we have found that slow neutron spectra have scaling and asymptotic properties [2].
Galoyan, A., Ribon, A., Uzhinsky, V.
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source