Results 1 to 10 of about 964,737 (198)

Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines [PDF]

Frontiers in Molecular Neuroscience, 2022
Our previous studies have clarified that red nucleus (RN) interleukin (IL)-6 is involved in the maintenance of neuropathic pain and produces a facilitatory effect by activating JAK2/STAT3 and ERK pathways.
Qing-Qing Yang, Qing-Qing Yang, Hao-Nan Li, Yu-Tong Xia, Xue Tian, Fan Feng, Jian Yang, Ya-Li Xu, Juan Guo, Xiao-Qi Li, Jun-Yang Wang, Xiao-Yan Zeng   +11 more
doaj   +2 more sources

Red Nucleus Excitatory Neurons Initiate Directional Motor Movement in Mice [PDF]

Biomedicines
Background: The red nucleus (RN) is a phylogenetically conserved structure within the midbrain that is traditionally associated with general motor coordination; however, its specific role in controlling directional movement remains poorly understood ...
Chenzhao He, Guibo Qi, Xin He, Wenwei Shao, Chao Ma, Zhangfan Wang, Haochuan Wang, Yuntong Tan, Li Yu, Yongsheng Xie, Song Qin, Liang Chen   +11 more
doaj   +2 more sources

Phylogenetic reduction of the magnocellular red nucleus in primates and inter-subject variability in humans [PDF]

Frontiers in Neuroanatomy
IntroductionThe red nucleus is part of the motor system controlling limb movements. While this seems to be a function common in many vertebrates, its organization and circuitry have undergone massive changes during evolution.
Martin Stacho, A. Niklas Häusler, Andrea Brandstetter, Francesca Iannilli, Hartmut Mohlberg, Christian Schiffer, Jeroen B. Smaers, Katrin Amunts, Katrin Amunts   +8 more
doaj   +2 more sources

Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3 [PDF]

Journal of Neuroinflammation, 2021
Background Our recent studies have identified that the red nucleus (RN) dual-directionally modulates the development and maintenance of mononeuropathic pain through secreting proinflammatory and anti-inflammatory cytokines.
Hao-Nan Li, Qing-Qing Yang, Wen-Tao Wang, Xue Tian, Fan Feng, Shu-Ting Zhang, Yu-Tong Xia, Jia-Xue Wang, Yuan-Wu Zou, Jun-Yang Wang, Xiao-Yan Zeng   +10 more
doaj   +2 more sources

Red nucleus and rubrospinal tract disorganization in the absence of Pou4f1 [PDF]

Frontiers in Neuroanatomy, 2015
The red nucleus is a neuronal population that plays an important role in forelimb motor control and locomotion. Histologically it is subdivided into two subpopulations, the parvocellular red nucleus located in the diencephalon and the magnocellular red ...
Jesus E. eMartinez-Lopez, Juan A. eMoreno-Bravo, M. Pilar eMadrigal, Salvador eMartinez, Salvador eMartinez, Eduardo ePuelles   +5 more
doaj   +2 more sources

The human brainstem’s red nucleus was upgraded to support goal-directed action [PDF]

Nature Communications
The red nucleus, a large brainstem structure, coordinates limb movement for locomotion in quadrupedal animals. In humans, its pattern of anatomical connectivity differs from that of quadrupeds, suggesting a different purpose.
Samuel R. Krimmel, Timothy O. Laumann, Roselyne J. Chauvin, Tamara Hershey, Jarod L. Roland, Joshua S. Shimony, Jon T. Willie, Scott A. Norris, Scott Marek, Andrew N. Van, Anxu Wang, Julia Monk, Kristen M. Scheidter, Forrest I. Whiting, Nadeshka Ramirez-Perez, Athanasia Metoki, Noah J. Baden, Benjamin P. Kay, Joshua S. Siegel, Hadas Nahman-Averbuch, Abraham Z. Snyder, Damien A. Fair, Charles J. Lynch, Marcus E. Raichle, Evan M. Gordon, Nico U. F. Dosenbach   +25 more
doaj   +2 more sources

Early red nucleus atrophy in relapse-onset multiple sclerosis. [PDF]

Hum Brain Mapp, 2021
AbstractNo study has investigated red nucleus (RN) atrophy in multiple sclerosis (MS) despite cerebellum and its connections are elective sites of MS‐related pathology. In this study, we explore RN atrophy in early MS phases and its association with cerebellar damage (focal lesions and atrophy) and physical disability.
Margoni M, Poggiali D, Zywicki S, Rubin M, Lazzarotto A, Franciotta S, Anglani MG, Causin F, Rinaldi F, Perini P, Filippi M, Gallo P.   +11 more
europepmc   +6 more sources

Constraint-Induced Movement Therapy Promotes Contralesional Red Nucleus Plasticity and Increases Bilateral Motor Cortex-to-Red Nucleus Projections After a Large-Area Stroke [PDF]

Behavioural Neurology
For decades, scientists have explored the patterns of neural network remodeling that occur after a stroke. Several studies have shown that both motor cortexes (MCs) undergo crucial remodeling after cerebral ischemia.
Peile Liu, Jian Hu, Beiyao Gao, Yan Hua, Ying Xing, Yulong Bai, Nan Liu   +6 more
doaj   +2 more sources

The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics [PDF]

Frontiers in Neural Circuits
The cerebellar output can trigger whisker movement through indirect projections that pass via several brainstem pre-motor nuclei before reaching the facial nucleus, which directly controls whisker movements in rodents.
Staf Bauer, Peipei Zhai, Nathalie van Wingerden, Hehe Zhao, Vincenzo Romano   +4 more
doaj   +2 more sources

Hearing in action; auditory properties of neurones in the red nucleus of alert primates [PDF]

Frontiers in Neuroscience, 2014
The response of neurones in the Red Nucleus pars magnocellularis (RNm) to both tone bursts and electrical stimulation were observed in three cynomolgus monkeys (Macaca fascicularis), in a series of studies primarily designed to characterise the influence
Jonathan Murray Lovell, Jonathan Murray Lovell, Judith eMylius, Henning eScheich, Michael eBrosch   +4 more
doaj   +2 more sources