Results 161 to 170 of about 257,904 (307)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Mass larval rearing technology of marine finfish in Japan

, 1996
With economic development and increased demand for high price fish, industrial scale marine finfish culture in Japan was started in 1960-1965 for yellowtail Seriola quinqueradiata. Sustainable supply of wild juvenile and development of floating cage with
Fukusho, Kunihiko
core  

Spatial distribution of selected coastal Sabkhas along the Southern Red Sea Coast of Egypt. [PDF]

Sci Rep
Younis NA, El-Habaak GH, El Hadek HH, Galal WF, Abdel-Hakeem M.   +4 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

reefgenomics/Red-Sea-RADSeq:

, 2021
Hume, Benjamin, Gosselin, Thierry, Buitrago-López, Carol, Barshis, Daniel J., Aranda, Manuel, Cardenas, Anny, Staubach, Fabian, Sawall, Yvonne, Voolstra, Christian R.   +8 more
core   +1 more source

Tissue-specific distribution of cytotoxic triterpene saponins in three Red Sea sea cucumbers. [PDF]

Sci Rep
Fayez S, Abed K, Moussa MS, Zohdy MN, Ali AM, El-Gohary MA, Awaad MM, Alshawarby NM, Sedky RI, Taha ME, El-Sayed TH, Abd Elhamied EM, Mahmoud NG, Serafeem TE, Chen PJ, Huang HC, Chen LY, Lai KH, El-Shazly M.   +18 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Investigation into the radioactivity of various natural and anthropogenic radionuclides in marine sediments from the Sudanese coastline of the Red Sea. [PDF]

Sci Rep
Abowslama E, Eltayeb M, Ibrahim KE, Elshaarani T, Babikir M, Osman E, Abdelgader G, Tarig N, Hassan N, Khalied M, Elbasheer F, AbdulRahman M, Osman A.   +12 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Evidence of Avian Predation on a Critically Endangered Elasmobranch, the Halavi Guitarfish (<i>Glaucostegus halavi</i>), in the Red Sea. [PDF]

Ecol Evol
Richardson EB, Hardenstine RS, O'Toole KA, McIvor AJ, Calabrese L, Laughlin SR, Scannell BJ, Cochran JEM, Berumen ML.   +8 more
europepmc   +1 more source