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Red Sea Bream Interleukin (IL)-1β and IL-8 Expression, Subcellular Localization, and Antiviral Activity Against Red Sea Bream Iridovirus (RSIV)

Fish and Shellfish Immunology, 2022
Interleukin-1 beta (IL-1β) is transcribed by monocytes, macrophages, and dendritic cells in response to activation of toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs) or cytokine signalling and causes a rapid inflammatory response to infection.
Do Hyung Kim, Hyun-Ja Han, Hye-Sung Choi
exaly   +3 more sources

Rapid Diagnosis of Red Sea Bream Iridovirus Infection Using the Polymerase Chain Reaction [PDF]

open access: yesDiseases of Aquatic Organisms, 1998
A simple and sensitive polymerase chain reaction (PCR) based assay is described for detection of the red sea bream iridovirus (RSIV) in infected fish. The assay involves amplification of a portion of the ribonucleotide reductase small subunit (RNRS) gene of the virus from DNA isolated from the spleen. The system was tested on red sea bream following an
Ikuo Hirono, Shinya Yamashita
exaly   +3 more sources

Analysis of the Transcriptomic Profiles of Mandarin Fish (Siniperca chuatsi) Infected With Red Sea Bream Iridovirus (RSIV)

Microbial Pathogenesis, 2023
Red sea bream iridovirus (RSIV) belongs to the family Iridoviridae, genus Megalocytivirus, which could widely infect marine fish, causing diseases and huge economic losses. Now it has been reported that RSIV was also detected in diseased mandarin fish.
Xiaodan Liu, Yanbing Zhang
exaly   +3 more sources

Protection of red sea bream Pagrus major against red sea bream iridovirus infection by vaccination with a recombinant viral protein

Microbiology and Immunology, 2010
Megalocytivirus infections cause serious mass mortality in marine fish in East and Southeast Asian countries. In this study the immunogenicity of crude subunit vaccines against infection by the Megalocytivirus RSIV was investigated. Three capsid proteins, 18R, 351R and a major capsid protein, were selected for use as crude subunit vaccines.
Hajime Shimmoto   +3 more
openaire   +3 more sources

Development of Red Sea Bream Iridovirus Concentration Method in Seawater by Iron Flocculation

Aquaculture, 2016
Abstract Pathogen dynamics in environmental water are considered to be highly associated with the prevalence of fish disease. To examine the dynamics of red sea bream iridovirus (RSIV), which has caused serious damage in marine aquacultures in Japan, we developed a highly sensitive and quantitative method by combining the viral concentration and real-
Toshihiro Nakai   +2 more
exaly   +2 more sources

Red sea bream iridovirus infection downregulates inflammation‐related genes in the spleen of rock bream (Oplegnathus fasciatus)

Journal of Fish Diseases, 2023
AbstractThis study investigated the kinetics of red sea bream iridovirus and host gene expression during infection in rock bream (Oplegnathus fasciatus), a species highly sensitive to the virus. After intraperitoneal injection of the viral solution at 104 TCID50/fish, the viral genome copy number in the spleen was 104.7 ± 0.2 and 105.9 ± 0.4 copies/μg ...
Chalermkwan Eurlaphan   +5 more
openaire   +2 more sources

Molecular Cloning, Characterization and Expression Analysis of Complement Components in Red Sea Bream (Pagrus Major) After Edwardsiella tarda and Red Sea Bream Iridovirus (RSIV) Challenge

Fish and Shellfish Immunology, 2018
The complement system plays an important role in immune regulation and acts as the first line of defense against any pathogenic attack. To comprehend the red sea bream (Pagrus major) immune response, three complement genes, namely, pmC1r, pmMASP and pmC3, belonging to the classical, lectin and alternative complement cascade, respectively, were ...
Shin-Ichi Kitamura   +2 more
exaly   +3 more sources

Evaluation of the Diagnostic Assays Detecting Red Sea Bream Iridovirus Infection at Different Severity Levels

Journal of Virological Methods
Red sea bream iridovirus (RSIV) is a highly contagious viral infection that affects various fish species and poses a significant threat to the global aquaculture industry. Thus, accurate and timely diagnosis is paramount for sustainable management of fish health.
Hee Jeong Kong, Ju-Won Kim
exaly   +3 more sources

Risk Assessment of Wild Fish as Environmental Sources of Red Sea Bream Iridovirus (RSIV) Outbreaks in Aquaculture

open access: yesDiseases of Aquatic Organisms
Red sea bream iridovirus (RSIV) causes substantial economic damage to aquaculture. In the present study, RSIV in wild fish near aquaculture installations was surveyed to evaluate the risk of wild fish being an infection source for RSIV outbreaks in cultured fish. In total, 1102 wild fish, consisting of 44 species, were captured from 2 aquaculture areas
Yasuhiko Kawato, Hidemasa Kawakami
exaly   +5 more sources

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