Results 91 to 100 of about 15,293,964 (305)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Nicaragua?s Red de Protección Social: An Exemplary but Short-Lived Conditional Cash Transfer Programme [PDF]
This country study investigates the history and eventual conclusion of Nicaragua?s conditional cash transfer programme, the Red de Protección Social (RPS).
Charity Moore
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Protección Social en Colombia: Red de Apoyo Social
Esta presentación fue comisionada por la Red de Reducción de la Pobreza y Protección Social del Diálogo Regional de Política para la Reunión Preparatoria celebrada los días 19 y 20 de octubre de 2000 en Washington, D.C.Bajo acceso a la seguridad social (
Cárdenas, Mauricio
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Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
¿Fe en la tecnología? Redes sociales, periodismo y la obra de James W. Carey
El artículo examina el optimismo depositado en las herramientas digitales de vanguardia. En la actualidad se las considera un medio para promover la participación social en procesos políticos mediante la producción de discusiones públicas ajenas a los ...
Alfredo Sepúlveda
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Compartiendo aprendizajes, el Proyecto RED SICTA
Locutores: Susana Fevrier y Luis Diego Solórzano Entrevistados: Armando Ferrufino, Jesús Pérez, Mariano Valladares, Efraín García, Marcelo Núñez, Israel Gálvez.Hoy nos enlazamos con productores, técnicos y especialistas que desde distintos países de ...
Instituto Interamericano de Cooperación para la Agricultura (IICA) +8 more
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