Results 111 to 120 of about 15,293,964 (305)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
La televisión conectada: ventajas e inconvenientes del estándar HbbTV
Cuadernos.info, 2012 El fenómeno de asimilación e interacción entre televisión e Internet está creciendo de forma significativa en los últimos años. Eso se está traduciendo en un impulso en la penetración de la televisión conectada e híbrida, hasta el punto de la irrupción ...
JOAN FRANCESC FONDEVILA GASCÓN
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Compartiendo aprendizajes, el Proyecto RED SICTA, Parte II
, 2010 Locutores: Susana Fevrier y Luis Diego Solórzano Entrevistados: Armando Ferrufino, Diana Savedra, Antonio Silva, Ángela Velázquez.Hoy productores de diversas partes de Centroamérica hablarán del Proyecto de Innovación Agrícola (RED SICTA) y sobre su ...
Instituto Interamericano de Cooperación para la Agricultura (IICA) +6 more
core
Los Angeles County Social Survey, 1993 (LACSS)
, 1993 The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +1 more source
So there I cast myself with Jesus into the sea of life
, 1976 Author's name used on publication is "Red I. Arobateau". At the end of the book there is a message by Arobateau titled "Is Homosexuality a Sin?"
Arobateau, Red Jordan
core +1 more source
Red Jordan Press - Loose pages
A selection of administrative papers including draft covers of books, correspondence related to Red Jordan Press, a Poem "Day Comes To Ten Thousand Studio Rooms", an invoice, an invoice book, a list of ISBNs, and a short index of new ...
Arobateau, Red Jordan
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
American Red Cross in Arkansas records
, 1917 This collection contains documents, photographs, and other items related to the history of the American Red Cross in Arkansas, from the founding of the earliest Arkansas chapters in 1917 to ...
American Red Cross.
core +1 more source