Results 131 to 140 of about 1,843,286 (302)

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

open access: yesAdvanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente   +5 more
wiley   +1 more source

Red vial cantonal y la autonomía de los gobiernos locales en su administración

open access: yes, 2021
Es incuestionable que el gran tema concerniente a la red vial en la coyuntura actual del desarrollo de los países, en ella incluida Costa Rica, es de trascendental importancia desde todo punto de vista. Contar con una infraestructura mínima que respalde las necesidades de transporte y comunicación de las comunidades en la época actual y ...
openaire   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Diagnóstico técnico del estado de las redes viales cantonales pavimentadas

open access: yesInfraestructura Vial, 2012
Los planes quinquenales son un instrumento útil de gestión vial, que permite planificar de manera ordenada las actividades necesarias para el mantenimiento y rehabilitación de la red, así como facilitar la estimación de los recursos requeridos para la ...
Sharline López R
doaj  

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady   +5 more
wiley   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

open access: yesAdvanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen   +13 more
wiley   +1 more source

CARACTERIZACIÓN DE LA ACCIDENTALIDAD VEHICULAR Y ANÁLISIS DE LAS CAUSAS EN LA PROVINCIA DE VILLA CLARA, CUBA

open access: yesDyna, 2012
La investigación que se presenta tiene como objeto de estudio las carreteras rurales de interés nacional en la provincia de Villa Clara, localizada en la región central de Cuba, con el propósito de analizar la seguridad vial en los tramos que componen ...
RENÉ A. GARCÍA DEPESTRE   +3 more
doaj  

Incorporación de factores socioeconómicos al análisis de vulnerabilidad del riesgo por inundación en vías usando un modelo geoespacial

open access: yesInvestigaciones Geográficas
Colombia por sus características geofísicas y ubicación en la zona tropical es propensa a fenómenos de inundación, que sumados a la vulnerabilidad de la red vial y la presencia permanente de población contiguamente a la vía, acrecientan la fragilidad ...
Alejandro Parra Saad   +3 more
doaj   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer   +10 more
wiley   +1 more source

Drug-Loaded, Bivalent-Bottle-Brush Polymers by Graft-through ROMP [PDF]

open access: yes, 2010
Graft through ring-opening metathesis polymerization (ROMP) using ruthenium N heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control Here we report the first bivalent-brush polymers, these ...
Burts, Alan O.   +6 more
core   +1 more source

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