Degradable fibrin hydrogels for transplantation of iPSC-derived retinal pigment epithelial cell monolayers. [PDF]
Marmorstein AD +11 more
europepmc +1 more source
Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro +11 more
wiley +1 more source
Photocatalytic Synthesis of 3,4-Dihydroquinolone from Tetrahydroquinolines by a High-Throughput Microfluidic System and Insights into the Role of Organic Bases. [PDF]
Ding S, Sun TY, Jiang H, Wu YD, Zhang X.
europepmc +1 more source
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz +10 more
wiley +1 more source
Transient cyanobacteria drive hydrostatic photogranulation but disappear during microbial succession. [PDF]
Galea-Outón S +2 more
europepmc +1 more source
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo +9 more
wiley +1 more source
Halide Perovskite-Chalcohalide Nanocrystal Heterostructures as a Platform for the Synthesis and Investigation of the CsPbCl3-CsPbI3 Epitaxial Interface. [PDF]
Livakas N +12 more
europepmc +1 more source
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira +18 more
wiley +1 more source
Characterization of Chemical Defensive Behavior and Associated Glands in the Destructive Invasive Longhorn Beetle Aromia bungii. [PDF]
Chen R +7 more
europepmc +1 more source
cDC1 Subtype‐Specific In Vivo Targeting of Liposomes
Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf +11 more
wiley +1 more source

