Results 111 to 120 of about 1,300,921 (289)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
O artigo centra-se na consolidação da rede educativa, em Portugal, a qual reduziu o número de escolas para cerca de metade, nas últimas duas décadas, explorando seus impactos económicos e educativos.
Pedro Abrantes
doaj
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FORMAÇÃO DE REDES DE TRABALHO COM ARTE EDUCAÇÃO EM CONTEXTOS ESCOLARES
Esta pesquisa elaborou uma cartografia artístico-cultural em rede, orientada pelo sistema de ensino, para promover modos de trabalho colaborativos entre a escola e a comunidade.
Danilo Moreira Xavier
doaj +1 more source
Meningkatkan Hasil Belajar Siswa Pokok Bahasan Alat Pernapasan Pada Manusia Menggunakan Media Gambar Pada Siswa Kelas V SDN Taningkola [PDF]
Tujuan penelitian ini adalah meningkatkan hasil belajar siswa kelas V SDN Taningkola melalui penggunaan media gambar. Penggunaan media gambar adalah pembelajaraan yang memanfaatkan gambar organ-organ tubuh manusia sehingga siswa dapat lebih mudah ...
Ratman, R. (Ratman) +2 more
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Tecnologia social: uma estratégia para o desenvolvimento [PDF]
Esta publicação apresenta reflexões de diversos representantes de instituições governamentais, do terceiro setor, da sociedade civil e de universidades sobre o tema da Tecnologia ...
Antonio E. Lassance, Jr. +13 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

