Results 121 to 130 of about 1,317,587 (309)
FORMAÇÃO DE REDES DE TRABALHO COM ARTE EDUCAÇÃO EM CONTEXTOS ESCOLARES
Revista da FundarteEsta pesquisa elaborou uma cartografia artístico-cultural em rede, orientada pelo sistema de ensino, para promover modos de trabalho colaborativos entre a escola e a comunidade.
Danilo Moreira Xavier
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Avaliação da substituibilidade de demanda e oferta na aviação internacional brasileira:
Revista de Defesa da ConcorrênciaContexto: a definição do mercado relevante no setor de aviação internacional varia entre as autoridades antitruste, com algumas focando nas rotas de origem-destino (O&D) e outras incorporando critérios mais amplos ou mais restritos.
Gabriel Oliveira de Alarcão +2 more
doaj +1 more source
Facebook: rede social educativa? [PDF]
, 2010 Actualmente, as redes sociais fazem parte da vida dos nossos alunos. O Facebook é, provavelmente, o principal sítio de encontro, comunicação, partilha e interacção de ideias e assuntos de interesse comum, entre os estudantes universitários.
Gonçalves, Vitor +1 more
core +1 more source
, 2017 O grande incremento na utilização de recursos tecnológicos, a que vimos a assistir, são melhor compreendidos quando contextualizados com as mudanças profundas que se observam a partir da última década do século passado. E estas são-no no âmbito da economia, da cultura, da comunicação e respetivas tecnologias, das políticas e das relações interpessoais,
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source