Results 111 to 120 of about 1,317,587 (309)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Brazilian experience in design for health: Interdisciplinary and Bioethics [PDF]
, 2009 Health design in Brazil has been characterized historically by replacing imported products with others that are locally manufactured on a small scale. The formation of interdisciplinary groups has never been submitted to specific norms, particularly at ...
Bonatti, Fernanda Alves da Silva +2 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
EnsaioO artigo centra-se na consolidação da rede educativa, em Portugal, a qual reduziu o número de escolas para cerca de metade, nas últimas duas décadas, explorando seus impactos económicos e educativos.
Pedro Abrantes
doaj
Polychromatic, Sexual Dimorphism and Redescription Species of Red Devil Amphilophus Amarillo [Stauffer & McKaye, 2002] in Sermo Reservoir, YOGYAKARTA [PDF]
, 2018 Red devil telah banyak diteliti karena variasi morfometrik dan kromatofora yang sangat tinggi, termasuk di dalamnya fenomena polikromatisme dan trofik polimorfisme.
Djumanto, D. (Djumanto) +2 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Initial approach to irst-time seizures in pediatrics [PDF]
, 2014 Objective: Prove that conducting complementary studies at laboratories and imaging studies are unnecessary in irst-time unprovoked seizures, since there is no change in the evolution and prognosis of the disease, as well as the study of our population ...
Chávez Rede, Martha Elena +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source