Results 131 to 140 of about 8,060 (258)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Burden, coping strategies, and family caregivers of older people with clinical frailty in the COVID-19 context. [PDF]
Rev Bras EnfermVitro L, Cruz MGDS, Horta ALM.
europepmc +1 more source
Redes Sociales Protocooperativas
, 2013 Este trabajo hace uso de la interdisciplinariedad con la biolog?a, para construir un concepto que explica la configuraci?n actual de la Web 2.0, su expansi?n y el crecimiento. Para ilustrar el proceso he utilizado la analog?a con las relaciones ecol?gicas que se pueden establecer sobre la base de las interacciones entre las especies neutras, positivas ...
openaire +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Technological arrangements for regulating access to healthcare: experience in the state of São Paulo. [PDF]
Rev Saude PublicaFreire MP +4 more
europepmc +1 more source
Redes sociales, participación e interacción social
Trabajo Social, 2009 Este artículo propone una reflexión sobre el concepto de red social en tres dimensiones: como proceso vincular intersubjetivo, como prácticas de colaboración y apoyo a quienes hacen gestión social, y como entrelazamiento de los significados que interpretan y explican la cotidianidad de individuos, grupos y organizaciones.
openaire +2 more sources
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source