Results 121 to 130 of about 838,035 (305)

Intervenção social em parceria – rede social de Silves [PDF]

open access: yes, 2016
Dissertação de Mestrado, Educação Social, Escola Superior de Educação e Comunicação, Universidade do Algarve, 2016A Intervenção Social em Parceria, no Concelho de Silves é o tema do presente Relatório de Atividade Profissional, desenvolvido no âmbito do
Santos, Rute Isabel Horta Justo dos
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

O Papel dos Irmãos nas Redes Sociais Pessoais de Idosos Portugueses [PDF]

open access: yes, 2015
Os estudos sobre redes sociais pessoais nas fases finais do ciclo vital têm focado vínculos específicos, sobretudo intergeracionais, tais como as relações entre pais e filhos ou avós e netos.
Monteiro, Daniela Alexandra Nascimento Pereira   +1 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Formação em rede para inclusão digital de educadores de telecentro [PDF]

open access: yes, 2013
Este artigo apresenta uma pesquisa sobre o curso on line de Formação em Rede para Educadores de Telecentros, implantados em todas as regiões do Brasil, com o objetivo de promover o acesso gratuito aos recursos das tecnologias da informação e comunicação ...
Okada, Alexandra   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Redes sociales

open access: yes, 2018
Diseño y ejecución del libro "redes sociales": ilustraciones, portada, texto y maquetación del mismo. El objetivo principal del libro es reflejar la cultura popular de la actualidad que vemos en las redes sociales y conservar esos momentos en el ...
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

MERCADO DE TRABALHO PARA ENFERMEIROS NO BRASIL: UM ESTUDO BASEADO NAS VAGAS DISPONÍVEIS NO LINKEDIN®

open access: yesRevista Baiana de Enfermagem
Objetivo: descrever as características do mercado de trabalho para enfermeiros no Brasil, baseado nas vagas disponíveis no LinkedIn®. Método: trata-se de uma pesquisa documental on-line, de abordagem quanti-qualitativa, realizada em julho de 2020.
Bruno de Campos Gobato   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy