Results 121 to 130 of about 11,964,360 (256)

10 ANOS DE PESQUISA DA REVISTA BRASILEIRA DE INOVAÇÃO SOB A ÓTICA DA BIBLIOMETRIA E DA REDE SOCIAL

open access: yesAdministração: Ensino e Pesquisa, 2014
Este artigo explorou a produção científica da Revista Brasileira de Inovação no período de 2002 a 2011. A referida pesquisa se norteou numa pesquisa bibliométrica e de rede social, utilizando-se de estatística descritiva em 100 artigos identificados.
Henrique César Melo Ribeiro   +1 more
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

PET REDE DE ATENÇÃO ÀS URGÊNCIAS E EMERGÊNCIAS NA LINHA DE CUIDADO DA HIPERTENSÃO ARTERIAL SISTÊMICA E DIABETES MELLITUS: RELATO DE EXPERIÊNCIA

open access: yes, 2014
INTRODUÇÃO: A hipertensão arterial sistêmica e o diabetes mellitus são dois dos principais fatores de risco para o desenvolvimento de doenças cardiovasculares, que constituem a principal causa de morbimortalidade na população brasileira.
Fruttoso, Maria Fernanda   +3 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A EXTENSÌO UNIVERSITÁRIA E A COLABORAÇÃO NO FORTALECIMENTO DA REDE DE CUIDADOS DA PESSOA COM DEFICIÊNCIA

open access: yes, 2018
INTRODUÇÃO: O presente relato tem por objetivo apresentar as ações do projeto de extensão da Universidade do Vale do Itajaí (SC) intitulado Grupo de apoio aos profissionais que compõem a rede de cuidado a pessoa com deficiência-ARAD, “visando o ...
Viana, Simone Beatriz Pedrozo   +9 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

O PET-SAÚDE NO APRIMORAMENTO DA REDE DE CUIDADO À PESSOA COM DEFICIÊNCIA NO MUNICÍPIO DE PONTAL DO PARANÁ-PR

open access: yes, 2014
INTRODUÇÃO: O Programa de Educação pelo Trabalho para a Saúde / Redes de Cuidado à Pessoa com Deficiência (PET-Saúde / Rede) tem como objetivo qualificar estudantes e profissionais para inserção ao Sistema Único de Saúde (SUS), de forma a contribuir para
Pereira, Luana Martins   +4 more
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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